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Cancer is asymptomatic during most of its pathogenesis. It is very difficult to see that a cancer is growing in a person, except for a few self-evident cases such as skin cancer. Its intangibility and year-, if not decade-long progression make cancer hard to diagnose until some symptoms warrant further…
New research has identified sections of DNA associated with altered regulation of gene expression underlying schizophrenia.
10 February 2017 | By Charles River
In this webinar, Charles River discuss the utilisation of CRISPR/Cas9 technology in drug discovery, with an emphasis on generation of in vitro models for high-throughput screening, and creating new mouse models...
The advent of next-generation sequencing (NGS) techniques has revolutionised transcriptomics research and opened numerous avenues for scientific and clinical applications. While reverse transcriptase quantitative real-time polymerase chain reaction (RT-qPCR) is still considered the gold standard of gene expression analysis, its high throughput, single-nucleotide resolution and ever-plummeting costs have made NGS…
4 July 2016 | By Victoria White, Digital Content Producer
MIT engineers have developed easily customisable RNA vaccines that can be manufactured in one week and have shown efficacy against ebola and H1N1 influenza...
28 June 2016 | By Victoria White, Digital Content Producer
Storm Therapeutics has secured £12 million in series A funding to identify small molecular drugs that target RNA-modifying enzymes...
The study of biochemistry provides molecular insights into how the human population ages, how diseases commence and progress, how molecular changes relate to disease remission and relapse, and how humans respond to treatments...
The toxicity and antiviral properties of 24 low-molecular-weight artificial RNases (artRNases) including peptides, peptidomimetics, N-alkyl-substituted 1,4-diazabicyclo[2.2.2]octane (DABCO) and a silver (I) complex with cystine were analysed for viruses containing single-stranded and double-stranded genomic RNA (the tick-borne encephalitis virus; TBEV and the influenza virus, respectively) in vitro and in vivo by…
1 June 2016 | By Victoria White, Digital Content Producer
Scientists have created a drug candidate that attacks and neutralises the RNA structure that causes spinocerebellar ataxia type 10 (SCA10)...
Neglected tropical diseases pose a significant threat to public health and affect nearly one billion people in tropical and sub-tropical regions throughout the world. There is a pressing need to identify new therapeutics for NTDs and many developed nations are participating in drug discovery efforts...
8 February 2016 | By SMi Group
SMi will open its doors to host RNA Therapeutics 2016 in just 1 week on 15th and 16th February in Central London...
2 February 2016 | By Victoria White
A team of scientists from Bath, Cambridge and the USA has identified a piece of non-coding RNA that stops cells turning cancerous...
11 January 2016 | By Victoria White
mRNA-based therapies are an innovative treatment approach that enables the body to produce therapeutic protein in vivo, opening up new treatment options for a wide range of diseases...
13 October 2015 | By Victoria White
An RNA editing technique called "exon skipping" has demonstrated preliminary success in treating Limb Girdle Muscular Dystrophy Type 2C in a new study...
17 September 2015 | By Victoria White
The new technique could be used to explore genetic mechanisms of resistance in the field of infectious disease and lead to new therapies...
