Featured Peptides: a promising alternative to opioids for chronic pain relief In an exclusive with Drug Target Review, researchers at the University at Buffalo explain how they developed a novel peptide that could be a future treatment for chronic inflammatory pain.
webinar Capturing biological complexity to empower biomarker discovery Sign up for this free webinar and discover how refined cell atlases can provide comprehensive roadmaps for health and disease.
UTX gene mutation “robs” individuals of natural cancer protection By Anna Begley (Drug Target Review)
Novel intestine chip enables effective in vitro study of COVID-19 therapies By Anna Begley (Drug Target Review)
Human iPSC-derived cardiomyocytes for cardiac proarrhythmic risk assessment By Anton Simeonov, Drug Target Review, Victoria Rees (Drug Target…
news UTX gene mutation “robs” individuals of natural cancer protection The UTX gene mutation was found to lead to an increased cancer risk, presenting a potential drug target for preventative therapies.
news Scientists explore CA2 neuron mitochondria for memory loss targets The team will receive $2 million over five years to investigate the CA2 brain region for the development of neurological therapies.
news Novel intestine chip enables effective in vitro study of COVID-19 therapies The intestine chip was infected with a coronavirus to test a variety of drugs, presenting a new method to investigate COVID-19 treatments.
news Researchers achieve DNA methylation removal in mouse models The study showed that DNA “de-methylation” activity can be targeted to anywhere in the DNA and may be a new therapeutic strategy.
news MicroRNA in red blood cells causes vascular damage in type 2 diabetes Researchers discovered that cardiovascular damage was caused by reduced microRNA-210 levels in patient cells and mice with type 2 diabetes.
news Soluble fibrinogen a potential target for neurodegeneration In a pre-clinical study, fibrinogen increased the death of mouse brain neurons, suggeting fibrin can have similar toxic effects on neurons.
ebook: High-Throughput Data Management in process development Cell Line Development and cell culture process teams, are you geared up to leverage the vast amount of data generated by high-throughput?
ebook: Optimise your high value cell lines As interest in biotherapeutic proteins grows, the need to reduce cell line development costs and the time to market is more critical than ever.
ebook: Why you need to digitally transform your R&D organisation Despite many companies considering digital transformation a top priority, research shows that 70% of digital transformation initiatives fail. In this ebook, we explore why and how the right approach can see your organisation succeed.
ebook: How automation makes labs more efficient We discuss how liquid handling automation supports drug discovery workflows & highlight opportunities to improve the efficiency and quality of these.
article Human iPSC-derived cardiomyocytes for cardiac proarrhythmic risk assessment Following Drug Target Review's webinar supported by Eurofins, speaker Dr Verena Albert answers the questions posed by the audience during… By Anton Simeonov, Drug Target Review, Victoria Rees (Drug Target…
article Are computer simulations the future of rapid COVID-19 drug development? Researchers have visualised SARS-CoV-2 protein dynamics using in silico methods. In this article, Navodya Roemer explains how a team from… By Navodya Roemer (University of Lincoln)
article AI & Informatics: Drug discovery and development – industry survey… View Drug Target Review's new infographic on the use of AI and informatics within early therapeutic development here. By Drug Target Review
article Targeting SARS-CoV-2 replication with inhibitors of lipid metabolism One approach towards efficient drug targeting efforts for COVID-19 is to repurpose medicines developed for other diseases. Here, Professor Christopher… By Professor Christopher Basler (Georgia State University)
article Improving drug discovery with advanced targeted proteomic monitoring workflows In this article, Professor Forest White, Department of Biological Engineering at MIT, and Dr Lauren Stopfer, Scientist at BioNTech, present… By Dr Lauren Stopfer (BioNTech), Professor Forest White (MIT)
Video The Science of Affimers Find out about the science behind Affimers - including why Affimers are superior to antibodies and details about our custom…