news
Inhibiting METTL3 enzyme combats acute myeloid leukaemia in mice
Scientists have developed a drug called STM2457 which inhibits a key enzyme involved in acute myeloid leukaemia.
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Translational Science
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Experimental drug shown to reverse effects of Alzheimer’s in mice
Oral doses of a new drug named CA administered to mouse models led to improvements in Alzheimer's disease, including memory.
news
Stem cell therapy repairs damage from dementia in mouse brains
Researchers have developed a stem cell therapy that could treat the damage caused by dementia by launching a repair response.
article
Targeting TNF to treat Dupuytren’s disease, frozen shoulder and POCD
Dr James Woody discusses off-patent indications for anti-TNF to address unmet patient needs in pain, inflammation and beyond.
news
MK-4482 antiviral effective against SARS-CoV-2 in hamster study
The drug MK-4482 decreased viral levels in the lungs of hamsters treated for SARS-CoV-2 infection, researchers have shown.
news
New gene therapy could preserve vision in retinitis pigmentosa patients
Delivering Txnip to mice with retinitis pigmentosa was an effective treatment, making this approach a potential gene therapy for the disease.
news
β-cell regeneration discovery could pave way for diabetes treatments
A key process in β-cell regeneration has been discovered by researchers who say this could lead to improved treatments for diabetes.
whitepaper
Application note: Evaluation of hepatic function in 3D culture
In vitro evaluation of hepatic function using a primary human hepatocyte 3D spheroid culture system
whitepaper
Application note: Hypoxia measurements in live and fixed cells
Hypoxia measurements in live and fixed cells using fluorescence microscopy and high-content imaging
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Application note: Automated imaging of cell viability
Automated fluorescence imaging and quantification of cell viability, with EVOS cell imaging system
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Application note: High-throughput imaging and analysis of spheroids
High-throughput fluorescence imaging and analysis of spheroids - tips, tricks, and tools to efficiently grow, stain, image, and analyze 3D cell cultures
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Application note: Oxidative Stress Measurements Made Easy
The advantages of detection of oxidative stress by high content analysis.
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Application note: Understanding Cell Death by High Content Analysis
Cell death is a process that occurs as both a part of normal tissue homeostasis and can be aberrantly regulated in some disease states, specifically cancer.
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Intellicyt iQue3 – Faster, Smarter Flow Cytometry
This advanced flow cytometry platform is a complete instrument, reagents and software solution streamlined to rapidly generate results not just data.
