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‘Are labs too cold for mice?’ researchers ask
19 April 2016 | By Victoria White, Digital Content Producer
Evidence is mounting that even mild chronic cold stress in lab mice is skewing results in studies of cancer, inflammation, and more...
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Oncology
Oncology is a branch of medicine that deals with the prevention, diagnosis and treatment of cancer.
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Resurrecting abandoned pancreatic cancer therapies
19 April 2016 | By Victoria White, Digital Content Producer
Results of a new study could help researchers develop more effective combination therapies and breathe new life into forgotten pancreatic cancer drugs...
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Positive preclinical results for lenvatinib + everolimus in kidney cancer
19 April 2016 | By Victoria White, Digital Content Producer
New preclinical data show the combination of lenvatinib and everolimus yield greater antitumour activity than either agent alone in kidney cancer...
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Infinity presents new preclinical data for PI3K-gamma inhibitor, IPI-549
18 April 2016 | By Victoria White, Digital Content Producer
IPI-549 is an orally administered immuno-oncology development candidate that selectively inhibits phosphoinositide-3-kinase gamma (PI3K-gamma)...
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Cancer cells ‘persuade’ healthy cells to help disease grow
14 April 2016 | By Victoria White, Digital Content Producer
Cancer cells use a mutant gene to coerce neighbouring healthy tissue into helping with the disease’s growth and spread, a major new study reports...
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Using mathematics to fight cancer
13 April 2016 | By Victoria White, Digital Content Producer
Mathematicians and physicians at the University of Bonn have developed a new model for cancer immunotherapy using mathematics...
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Genetic link confirmed between DCIS and development of invasive breast cancer
12 April 2016 | By Victoria White, Digital Content Producer
The discovery means that a family history of DCIS could be as important to assessing a woman’s risk as a history of invasive breast cancer...
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Cancers can resist treatment by ‘stealing’ blood vessels
8 April 2016 | By Victoria White, Digital Content Producer
A new study is the first to show that tumours can become resistant to drugs over time by learning to steal normal blood vessels from surrounding tissue...
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Children with cancer to be offered gene testing in personalised treatment initiative
31 March 2016 | By Victoria White
Children with cancer will be offered testing for genetic mutations in their tumours as part of an initiative to personalise children’s cancer treatment...
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Explaining CAR T-cell therapy
23 March 2016 | By Dr John Maher, Principal Investigator, National Institute for Health Research (NIHR) Biomedical Research Centre (BRC) at Guy’s and St Thomas’ and Kings College London
Here, Dr John Maher of the NIHR BRC at Guy's and St Thomas' and Kings College London discusses CAR T-cell therapy and the exciting frontier the technique has opened up in the battle against cancer...
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Classifying brain tumours to improve diagnoses
Brain tumours are complex cancer types, arising in many unique forms, each having varying survival rates and differing methods of treatment. Many brain tumours are difficult to clearly diagnose, leading to poor patient prognoses. Although they are mainly diagnosed by analysing morphological appearance, this does not closely correlate with the…
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SRI International awarded $19.8m to develop cancer preventive vaccines
15 March 2016 | By Victoria White
A division of SRI International will conduct preclinical studies to assess the efficacy of compounds or vaccines for preventing invasive-cancer development...
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Blueprint Medicines to develop novel therapeutics targeting immunokinases
15 March 2016 | By Victoria White
Under a collaboration with Roche, Blueprint Medicines will lead preclinical research and development through to Phase I proof of concept...
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HRX9 shows promise as a treatment for mesothelioma
14 March 2016 | By Victoria White
After three weeks' treatment with HXR9, human mesothelioma tumours in mice stopped growing, with a complete loss of tumour blood vessels and widespread cancer cell death...
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Collaboration to further explore the role of citrullinated proteins in cancer
11 March 2016 | By Victoria White
Scancell is to collaborate with the Karolinska Institutet to explore the scientific and clinical role of citrullinated proteins in the treatment of cancer...
