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Oncology is a branch of medicine that deals with the prevention, diagnosis and treatment of cancer.
A pioneering team of scientists from Rice University has discovered that a particular combination of chemotherapeutics, including mitocans that target mitochondria, form a powerful treatment for acute myeloid leukaemia patients.
The involvement of clathrin in the development of liver cancer has been described for the first time, which could lead to more targeted therapy.
A novel CDK8 inhibitor has been developed by scientists at Ryvu Therapeutics. Dr Krzysztof Brzozka showcases this molecule and explains the R&D behind it.
A team has imaged the process that the body uses to stabilise DNA, which could be used to develop therapies for conditions such as cancer.
A new study has shown the specific cellular mechanisms that limit the ability of CD8 T cells to infiltrate the tumour microenvironment, which could guide new immunotherapeutic strategies in cancer.
Regulator genes and proteins have been identified on circulating tumour cells in mice which allow them to target other organs in the body.
Peptide-based nanoparticles have been designed which can suppress pancreatic cancer growth without the toxic side effects.
A new mechanism by which cancer cells become resistant to chemotherapy has been found which could lead to a new target for drugs.
A study has demonstrated that the stiffness of cells indicates whether a tumour will spread and inducing this state could help to avoid metastasis.
A study has found a selective inhibitor for an enzyme that allows cancer cells to mutate and become resistant to treatments.
A team has used viral gene editing and CRISPR to form a system that marks tumours for destruction, potentially improving immunotherapies.
Cells containing Meflin play a role in restraining the progression of pancreatic cancer and could lead to new therapies against the disease.
A new platform has the potential to better understand what dictates the invasive behaviour of brain tumours.
Researchers have discovered that a specific subset of gamma delta T cells can be found in higher numbers of breast cancer survivor tissue, indicating its role in fighting the condition.
The researcher Sir Peter Ratcliffe and two others have been jointly awarded the Nobel Prize for Physiology or Medicine 2019.
