news
Exosomes identified as the missing link to insulin resistance
Researchers have identified exosomes as the missing link in diabetes...
List view / Grid view
miRNAs
news
Gene-regulatory factors improve pancreatic cancer treatment
Researchers have identified two molecules that can improve the response of pancreatic cancer to a common chemotherapy drug and also predict the prognosis of pancreatic cancer patients...
news
Micro-gene protects the brain from developing epilepsy
A tiny microRNA has been shown to play a beneficial role in protecting the brain from epileptic seizures in specially engineered transgenic mice.
article
Valid biomarker signatures from liquid biopsies – how to standardise NGS
The advent of next-generation sequencing (NGS) techniques has revolutionised transcriptomics research and opened numerous avenues for scientific and clinical applications. While reverse transcriptase quantitative real-time polymerase chain reaction (RT-qPCR) is still considered the gold standard of gene expression analysis, its high throughput, single-nucleotide resolution and ever-plummeting costs have made NGS…
news
ReNeuron pursues glioblastoma multiforme as target for exosome platform
9 June 2016 | By Victoria White, Digital Content Producer
ReNeuron selected glioblastoma multiforme based on evidence of tumour-inhibiting activity from early preclinical studies with the exosome technology...
news
Restoring chemotherapy sensitivity in resistant pancreatic cancer
27 May 2016 | By Victoria White, Digital Content Producer
By increasing the level of miR-374b, researchers have restored chemotherapy sensitivity to pancreatic cancer cells that had developed resistance...
news
Targaprimir-96 successfully targets breast cancer RNA
10 May 2016 | By Victoria White, Digital Content Producer
Scientists have designed a drug candidate, Targaprimir-96, that decreases the growth of tumour cells in animal models of triple negative breast cancer...
news
miR551b identified as a promising target for ovarian cancer
6 May 2016 | By Victoria White, Digital Content Producer
The microRNA miR551b has been shown to impact STAT3 protein levels, contributing to resistance to cell death and increased proliferation of cancer cells...
news
miR-155 deletion prevents diet-induced obesity in mice
23 March 2016 | By Victoria White
In a study, despite eating a high-fat diet for 3 months, miR-155 knockout mice did not become obese and had enhanced metabolic rates...
article
Pushing the limits of protein expression with miRNAs
Biopharmaceuticals are highly complex protein drugs such as antibodies, cytokines and peptide hormones, which are used for a variety of indication areas, including immunology, neurology, metabolic diseases and cancer. These modern protein drugs may hinder progression of a disease, ease symptoms or assure – in the case of chronic diseases…
news
Nanoparticles inhibit liver cancer tumour growth in study
26 January 2016 | By Victoria White
Scientists from UTSW have crafted synthetic "dendrimer" nanoparticles that are able to provide a tumour-suppressing effect without further damaging the liver or neighbouring tissue...
news
Preclinical data for ReNeuron’s exosome nanomedicine platform published
12 January 2016 | By Victoria White
ReNeuron is researching the therapeutic potential of exosomes derived from its proprietary stem cell lines. The Company is also exploring the potential of its exosomes as a delivery system for gene therapy treatments...
news
InteRNA Technologies secures final extension Series A financing
30 October 2015 | By Victoria White
InteRNA says the proceeds of this financing will be used to progress several of its lead product candidates...
news
International consortium CANCER-ID to develop novel biomarker technologies in cancer
23 April 2015 | By Victoria White
Bayer and UKE are the main coordinators of a new international consortium, CANCER-ID, to develop novel blood-based biomarker technologies in cancer...
