news
Immunotherapy and gene therapy combination shows promise against brain tumours
The outlook for brain tumour patients is pretty negative, with the median survival rate for patients with glioblastoma multiforme, or GBM, a mere 14.2 months.
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Drug Targets
A drug target is anything within a living organism to which a drug is directed and/or binds, resulting in a change in its behaviour or function.
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DiscoverX In Vitro Pharmacology Services – Simplify Your Drug Discovery Workflow
21 October 2016 | By DiscoverX Corporation
Monitoring cellular drug penetration and drug-target interaction enables assessment of compound efficacy and confirmation of mode of action...
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Fibromyalgia pathogenesis provides drug target clues
Fibromyalgia (FM) has been described as a condition of heightened generalised sensitisation to sensory input presenting as a complex of symptoms dominated by chronic widespread pain characterised by hyperalgesia and allodynia. A range of co-morbidities of variable intensity, such as fatigue, sleep disturbance, cognitive impairment, anxiety and depression, are often…
whitepaper
Poster note: Target discovery program in systemic sclerosis
Novel candidate drug targets for systemic scleroderma were identified using RNAi in phenotypic assays in scleroderma patient-derived fibroblasts...
whitepaper
App note: Struggling with ERK phosphorylation in GPCR research?
This short, easy-to-read Application Note goes over the background and basics of ERK signaling in multiple GPCR models...
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Bio-Rad Bio-Plex Multiplex Immunoassay System
4 August 2016 | By Bio-Rad Laboratories
The Bio-Plex System offers high-performance readers, industry-leading software, and sensitive assays in ready-to-use or custom configurations, enabling you to obtain high-quality data from limited samples...
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Bio-Rad CFX96 Touch™ Real-Time PCR Detection System
4 August 2016 | By Bio-Rad Laboratories
The CFX96™ Optical Reaction Module converts the C1000 Touch™ Thermal Cycler chassis into the powerful and precise CFX96 Touch Real-Time PCR Detection System...
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Bio-Rad S3e™ Cell Sorter
4 August 2016 | By Bio-Rad Laboratories
The Bio-Rad automated S3e™ Cell Sorter allows you to perform simple 1–4 colour sorts in less than 30 minutes and greatly enhances your experimental success...
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IntelliCyt MultiCyt Reagent kits
28 July 2016 | By IntelliCyt Corporation
Robust mix and read kits for cell- and bead-based screening applications...
news
A potential new target for scratching out itch
20 July 2016 | By Victoria White, Digital Content Producer
Scientists have discovered how sensory nerve cells work together to transmit itch signals from the skin to the spinal cord...
news
Manipulating HCN channels could lead to new depression treatments
12 July 2016 | By Victoria White, Digital Content Producer
Using gene therapy, scientists from Northwestern Medicine have identified a target in the brain that could lead to new treatments for depression...
news
Ovarian cancer signalling hub points to target for limiting metastasis
10 July 2016 | By Cold Spring Harbor Laboratory
Researchers at Cold Spring Harbor Laboratory have discovered new insights into signalling events that underlie metastasis in ovarian cancer cells...
news
NEAT1 identified as potential therapeutic target in the fight against cancer
4 July 2016 | By Victoria White, Digital Content Producer
Scientists have shown that NEAT1, a non-coding RNA, plays an important role in the survival of highly dividing cells - and in particular of cancer cells...
news
Heptares and leadXpro to employ powerful new techniques for GPCR structure determination
29 June 2016 | By Victoria White, Digital Content Producer
Heptares Therapeutics and leadXpro are to employ powerful new approaches for the determination of high-resolution X-ray structures of GPCRs...
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EMD Millipore: Verifi(Ab)le – Neuroscience Antibodies
28 June 2016 | By Merck KGaA
EMD Millipore is continually developing and refining tools and technologies for the study of neuroscience. Researchers can count on our comprehensive portfolio of dependable, high-quality solutions for elucidating questions related to neuroscience...
