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Assay of clotting ability accurately predicts need for transfusion in trauma patients
A new test of blood clot strength has the potential to identify patients who are most in need of a substantial blood transfusion.
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New genes identified in children linked to stress & bipolar disorder
Genetic alterations that can be modulated by stress have been identified in children at high risk for bipolar disorder, according to a new study...
news
New method for early screening of colorectal cancer
A highly sensitive method that can detect even the earlier stages of colorectal cancer has been developed by researchers in Japan.
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Novel method to detect toxic effects of chemicals could reduce need for animal testing
Traditional toxicological investigations performed on animals (in vivo) are expensive, time-consuming and may cause animal suffering.
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Obesity behind surge in kidney cancers
Kidney cancer rates have increased by 40% over the last 10 years in the UK, and the rise is expected to continue. An estimated 20,000 kidney cancer cases have been caused by obesity over the last decade in England, according to new figures from Cancer Research UK.
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Biologic treatments for inflammatory bowel disease help heal the intestine
Although anti-inflammatory treatments are quite effective at reducing symptoms in patients with Crohn's disease and ulcerative colitis, the mucosal lining of the intestine often remains ulcerated, and many patients still ultimately require surgery.
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JPND launches €23 million call for neurodegenerative disease research
Neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease are a global health, economic and social emergency.
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ESCMID-ASM to review antimicrobial development process
27 June 2016 | By European Society of Clinical Microbiology and Infectious Diseases (ESCMID)
ESCMID and ASM are jointly organising a conference to help researchers accelerate the development of new antimicrobials for drug-resistant infections...
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Analysis of human stem cell interactions at the single cell resolution
As a stem cell divides, two daughter cells are produced that either possess stem cell characteristics or become a cell with a more specialised function. Cellular markers have been identified that can be used to describe the phenotype of all stem cell progeny. However, the development of tools that allow…
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Advanced techniques and applications of LC-MS in small molecule drug discovery
A key process in drug discovery is the ability to identify new drug candidates by screening chemical libraries of small molecules, natural products or extracts against a biological target and selecting lead compounds with desirable therapeutic effects. Medicinal chemistry has the challenging role of not only ensuring that the chemical…
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Proteogenomic breast cancer study provides insight into potential therapeutic targets
26 May 2016 | By Victoria White, Digital Content Producer
Scientists have completed the first large-scale proteogenomic study of breast cancer, linking DNA mutations to protein signalling...
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The threat of antibiotic resistance
25 April 2016 | By Victoria White, Drug Target Review
We've created an infographic on the threat of antibiotic resistance, highlighting some of the recommendations made by the Review on Antimicrobial Resistance to date...
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Demands in medical automation technology brings two prominent players close
22 April 2016 | By Snehal Chougule, Allied Market Research
Here, Snehal Chougule discusses Trajan's recent investment in automation solution company, LEAP Technologies Inc...
whitepaper
Whitepaper: Affimer® reagents facilitate affinity chromatography purification of proteins
Purification of tag-free proteins, a vital step for many research and industrial applications...
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Researchers identify PHGDH inhibitor to target serine biosynthesis in cancer
8 March 2016 | By Victoria White
Researchers have shown that CBR-5884 was able to inhibit cell proliferation of breast cancer and melanoma cells lines that overexpress PHGDH...
