news
TSRI scientists use ligands to turbocharge drug discovery
Ligands are useful tools for studying how proteins work in cells and could lead to the development of new drugs.
List view / Grid view
The Scripps Research Institute (TSRI)
news
TSRI’s rat study shows how brain stores memories
A new study led by scientists at the Scripps Research Institute (TSRI) sheds light on how the brain stores memories.
news
TSRI scientists develop vaccine against fatal prescription opioid overdose
30 November 2016 | By Niamh Louise Marriott, Digital Editor
Scientists at The Scripps Research Institute have developed a vaccine that blocks the pain-numbing effects of the opioid drugs in animal models...
news
TSRI study shows how Ebola adapted to better target human cells
3 November 2016 | By Niamh Louise Marriott, Digital Content Producer
A new study csuggests that Ebola virus gained a genetic mutation during the 2013 – 16 epidemic that appears to have helped it better target human cells...
news
Mkx gene revealed as crucial for keeping tendons healthy
14 July 2016 | By Victoria White, Digital Content Producer
The Scripps Research Institute scientists behind the study say their findings may bring doctors closer to using gene therapies to grow and repair tendons...
news
Scientists stabilise HIV structure and design potential vaccine candidates
29 June 2016 | By Victoria White, Digital Content Producer
Scientists have described a strategy to stabilise an important HIV structure and potentially create HIV lookalikes for large-scale vaccine production...
news
GlyRS identified as a possible new breast cancer drug target
27 June 2016 | By Victoria White, Digital Content Producer
Scientists have identified a protein, called GlyRS, that launches cancer growth and appears to contribute to higher mortality in breast cancer patients...
news
A powerful new method for finding drug candidates
15 June 2016 | By Victoria White, Digital Content Producer
Scientists from The Scripps Research Institute have developed a powerful new method for finding drug candidates that bind to specific proteins...
news
Compound erases RNA defect that causes spinocerebellar ataxia type 10
1 June 2016 | By Victoria White, Digital Content Producer
Scientists have created a drug candidate that attacks and neutralises the RNA structure that causes spinocerebellar ataxia type 10 (SCA10)...
news
Painkiller celecoxib slows cancer growth rate
26 May 2016 | By Victoria White, Digital Content Producer
Scientists have found that a widely prescribed painkiller, celecoxib, slows the growth rate of a specific kind of cancer in animal models...
news
Targaprimir-96 successfully targets breast cancer RNA
10 May 2016 | By Victoria White, Digital Content Producer
Scientists have designed a drug candidate, Targaprimir-96, that decreases the growth of tumour cells in animal models of triple negative breast cancer...
news
Designing therapeutic warheads that target cancer cells
10 May 2016 | By Victoria White, Digital Content Producer
Scientists have designed dozens of molecular “warheads” that can detect a key biomarker of cancer and could be developed into a new class of drug candidates...
news
Scientists discover the cause of appetite loss during illness
5 May 2016 | By Victoria White, Digital Content Producer
Scientists have discovered how interleukin 18 hijacks a brain circuit and reduces appetite. The research points to potential targets for treating appetite loss...
news
Predicting cell changes that affect breast cancer growth
3 May 2016 | By Victoria White, Digital Content Producer
Scientists have shown how small structural changes in a key breast cancer receptor can produce predictable effects in curbing or accelerating cancer growth...
news
First glimpse of an immature HIV-neutralising antibody
6 April 2016 | By Victoria White
Scientists have described the first-ever immature antibody found in a powerful class of immune molecules effective against HIV. TSRI biologist Jiang Zhu called the antibody a “teenager” and said it gives scientists a unique view of the steps needed to prompt the immune system to effectively target HIV...