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Innovative algorithm could help advance single-cell genomics
Researchers have developed a novel algorithm, “scArches”, that can compare data on single-cell genomics to better understand diseases.
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Inhibiting Asc-1 protein function could present new drug target for obesity
Researchers have shown that loss of Asc-1 function could help obese patients maintain a healthy metabolism.
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CNS target could lead to development of drugs for diabetes
Researchers have shown that a GLP-1/GIP dual-agonist targets the GIP receptor in the brain and CNS to reduce body weight and food intake.
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Larval protein could suppress inflammatory reactions, say researchers
A study has revealed that a protein of roundworm larvae which needs to invade the intestines of rodents to survive could be used to control inflammation.
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Novel label-free method enables imaging of metabolites
A label-free imaging technology has been developed by researchers, allowing them to investigate biomolecules such as metabolites, aiding in the study of drugs.
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Study identifies brain stiffness as crucial for neurogenesis
A research team has shown that a key difference between neurogenic and non-neurogenic tissues is cross-linking proteins causing stiffness, a discovery that could be used to create new brain injury therapies.
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Using AI for error correction in single cell analyses
Researchers have developed algorithms that make it possible to predict and correct cells to identify genes...
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Arming T-cells to channel aggression against cancer
Scientists have armed immune cells with a new surface molecule that causes them to respond aggressively when they encounter a protein that tumours actually use to camouflage themselves from the immune system. Researchers from the Helmholtz Zentrum München and various partners introduced the method in ‘Cancer Research’.
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Deep Learning predicts hematopoietic stem cell development
Autonomous driving, automatic speech recognition, and the game Go: Deep Learning is generating more and more public awareness.
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Screening In-Depth Focus 2016
In this Screening In-Depth Focus, scientists from the Assay Development and Screening Platform of Helmholtz Zentrum München provide an overview of different high-throughput screening (HTS)-applicable assay types that can be applied to drug discovery campaigns. Plus an interview with Lee Babiss, CEO of drug discovery firm X-Rx, on the benefits…
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Smart drug uses pancreatic hormone to clear fat from liver and blood
17 October 2016 | By Niamh Louise Marriott, Digital Content Producer
An efficient and safe medicine, which would reverse obesity, insulin resistance, fatty liver and atherosclerosis remains a major scientific challenge...
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EBV-derived microRNAs silence immune alarm signals of the host cell
5 October 2016 | By Niamh Louise Marriott, Digital Content Producer
The virus drives production of small molecules, so-called microRNAs, which suppress alarm signals sent out by the infected cell...
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Methanobactin – an agent against Wilson’s disease
21 June 2016 | By Victoria White, Digital Content Producer
In an experimental model of Wilson's disease, the peptide, called methanobactin, has already proven superior to conventional medicines...
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LMP2A protein camouflages Epstein-Barr virus in human cells
15 June 2015 | By Victoria White
Scientists at Helmholtz Zentrum München have discovered that Epstein-Barr virus (EBV) conceals itself in human cells using the LMP2A protein.
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Mini-breast grown in petri-dishes – a new tool for cancer research
12 June 2015 | By Victoria White
Scientists have created 3D organoid-structures that recapitulate normal breast development and function from single patient-derived cells...