Function of protein involved in liver cancer discovered 30 October 2019 | By Rachael Harper (Drug Target Review) The involvement of clathrin in the development of liver cancer has been described for the first time, which could lead to more targeted therapy.
First detailed 3D image of astrocytes produced by researchers 30 October 2019 | By Victoria Rees (Drug Target Review) Researchers have compiled images to create the first detailed 3D models of astrocytes, which could be used in the development of therapeutics to aid their function.
Clues discovered for why MYH9 gene mutations cause human disorders 29 October 2019 | By Rachael Harper (Drug Target Review) A new study has demonstrated for the first time that mutations that affect myosin motor activity result in slower cell movements in vivo.
Inflammatory protein can protect against the spread of herpes virus 29 October 2019 | By Rachael Harper (Drug Target Review) A new study that examined the protein IL-36γ could aid in the development of novel therapeutics to protect against STIs.
Protein vital for T cell formation and function revealed 29 October 2019 | By Victoria Rees (Drug Target Review) Researchers have discovered a protein that is required for T cell biological processes; they have also demonstrated the mechanism behind the protein.
Intervening tau accumulation could halt progression of Alzheimer’s 29 October 2019 | By Victoria Rees (Drug Target Review) A group of researchers has found that tau misfolding is not harmful in itself, but instead the cellular processes its affects kills neurons.
Genetic mutation in monkeys identified as cause of Bardet-Biedl Syndrome 28 October 2019 | By Victoria Rees (Drug Target Review) A study has revealed that in rhesus monkeys, a genetic mutation could be the cause of Bardet-Biedl Syndrome, providing a way to study the disease and develop therapies.
Researchers reveal how body repairs damaged DNA 28 October 2019 | By Victoria Rees (Drug Target Review) A team has imaged the process that the body uses to stabilise DNA, which could be used to develop therapies for conditions such as cancer.
Protective antibody discovery could lead to better flu treatments 28 October 2019 | By Rachael Harper (Drug Target Review) Researchers have identified a set of three antibodies that they suggest could become the basis for a new antiviral treatment and inform the development of new influenza vaccines.
Rhomboid protease role observed using dynamic imaging 28 October 2019 | By Rachael Harper (Drug Target Review) Researchers have been able to watch rhomboid proteases in a native lipid environment which may be useful for the development of Parkinson's and malaria medication.
Microprotein revealed to regulate cell stress by study 25 October 2019 | By Victoria Rees (Drug Target Review) Researchers have discovered a microprotein that acts as a regulator of cell stress, which could be used in developing therapies for a wide range of conditions.
New antiviral drug demonstrated to effectively treat influenza in models 25 October 2019 | By Rachael Harper (Drug Target Review) A new antiviral drug has been reported in a study that researchers believe has high clinical potential as a next-generation influenza drug.
T cell immune system regulator identified by researchers 25 October 2019 | By Victoria Rees (Drug Target Review) A new study has discovered two enzymes which regulate a biological switch that controls the immune system, providing the potential to develop targeted therapies.
New discovery leads to greater understanding of Alzheimer’s disease 25 October 2019 | By Rachael Harper (Drug Target Review) A new study has linked an inflammatory protein to impaired memory mechanisms which could lead towards finding a more effective treatment for Alzheimer's.
Polymerised oestrogen shown to protect nervous system cells 24 October 2019 | By Victoria Rees (Drug Target Review) Researchers have polymerised oestrogen using a new approach and found it is effective at protecting and regenerating nervous system cells in vitro.
