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In this application note, PerkinElmer demonstrate the utility of an AlphaLISA assay for screening biotherapeutic antibodies and compounds that block binding of human PD-1 and PD-L1.
Scientists at Massachusetts General Hospital (MGH) have identified how a type of lung cancer co-opts a portion of the immune system via bone marrow to increase tumour progression.
Researchers have engineered T-cells in the laboratory to combat tumours...
A new generation DNA-based Zika vaccine is the first to demonstrate both safety and the ability to elicit an immune response against Zika in humans...
A new biomedical tool has been developed using nanoparticles that deliver transient gene changes to targeted cells...
Researcher have shown how a mRNA molecule known as Lethal-7 serves as a molecular control hub to direct the function of cytotoxic T lymphocytes...
Scientists have synthesised a complex sugar structure that specifically binds to the tumour protein Galectin-1...
Scientists have identified a Par-4 amino-terminal fragment that is released by diverse therapy-sensitive cancer cells...
Finnish researchers have found that an accumulation of gene mutations, similar to those typically seen in the development of cancer, also occur in some patients with rheumatoid arthritis.
A new study has identified how exposure to sunlight alleviates symptoms of eczema by triggering the release of a compound in the skin that dampens inflammation.
Patients who have aggressive prostate cancer could be identified by a highly accurate and simple blood test, according to a new study.
The new study suggests that defects in Tregs could be responsible for alopecia areata, a common autoimmune disorder that causes hair loss, and could potentially play a role in other forms of baldness, including male pattern baldness
The science behind harnessing the immune system to fight cancer is complicated, but a University of Rochester Medical Center laboratory discovered a simple, practical way to use light and optics to steer killer immune cells toward tumours.
Viruses are notorious for taking over their host's operations and using them to their own advantage. But few human viruses make themselves quite as cozy as the Epstein-Barr virus, which can be found in an estimated 9/10 humans without causing any ill effects. That is, until this virus causes mononucleosis…
A new study has identified a previously undescribed role for a type of unconventional T cell with the potential to be used in the development of new therapies for infection and cancer.
