news Novel label-free exosome profiling method shows success at detecting cancer 29 October 2021 | By Victoria Rees (Drug Target Review) A new label-free technique has been developed for molecularly specific exosome biosensing in diagnostics and biomarker detection.
news Immune cells found co-operating to capture and “eat” bacteria 13 September 2021 | By Anna Begley (Drug Target Review) Researchers have identified a spider-like antibacterial mechanism by immune cells that could inspire Staphylococcus aureus treatments.
webinar Imaging Mass Cytometry™ of malignant tissue architecture: rare single cells to structured multi-cellular communities 14 April 2021 | By Fluidigm Watch our free on-demand webinar to learn more about using Imaging Mass Cytometry™ (IMC™) to measure over 40 protein targets with subcellular resolution.
article A novel approach to unravelling the mysteries of Alzheimer’s 16 December 2019 | By Dr Sean Devenish (Fluidic Analytics), Professor Tuomas Knowles (University of Cambridge) The heterogenous and dynamic nature of protein aggregates makes them a particularly challenging class of structures to study. In this article, Professor Tuomas Knowles and Dr Sean Devenish present a novel approach to studying protein structures that could aid in understanding the complexities of Alzheimer’s disease and identify future therapeutic…
news New discovery shows ability of Schwann cells to generate myelin 8 July 2019 | By Drug Target Review Research from Oregon Health & Science University could lead to new therapies to heal nervous system disorders.
news Diverse Parkinson’s-related disorders may stem from different strains of same protein 10 May 2018 | By Drug Target Review Researchers found that the type of brain cell afflicted in Parkinson’s-related brain disorders dictates which pathological form of α-synuclein (α-syn) protein becomes the disease culprit.
news New weakness found in most common childhood malignant brain tumour 7 December 2017 | By Drug Target Review A new weakness found in medulloblastoma could lead to more personalised medicine and improved treatment for some patients.
news New Alzheimer’s animal model more closely mimics human disease 5 December 2017 | By Drug Target Review Researchers have found that amyloid-? facilitates the interaction between the plaques and abnormal tau.
article Expert view: Advances in NGS technology 13 September 2017 | By Dumitru Brinza (Thermo Fisher Scientific) The multiplex and high-throughput capabilities of next-generation sequencing (NGS) allow researchers to study an immense number of DNA/RNA molecules per run, bringing opportunities to study biological or clinical research questions that could not be addressed before...
news New research highlights key differences between mice and men 4 July 2017 | By Drug Target Review Research from King’s College in London, UK, and Lund University in Sweden could explain why diabetes drugs that have worked in animal experiments are not equally successful in humans. The researchers discovered differences – as well as hitherto unknown similarities – in the function of insulin-producing beta cells.
news Human neurons in mouse brains are more susceptible to Alzheimer’s pathology 28 February 2017 | By Niamh Marriott (Drug Target Review) Cells behave differently when removed from their environments, just as cells that develop in cultures do not behave like cells in living creatures.
article Tackling the spread of pathogens in transport hubs 13 December 2016 | By Ilpo Kulmala (VTT Ltd) Ilpo Kulmala, Principal Scientist at VTT Ltd, explains the role that transportation plays in the spread of infectious diseases...
news Scientists develop Chlamydia vaccine 20 July 2016 | By Niamh Louise Marriott, Digital Content Producer Scientists have developed the first widely protective vaccine against chlamydia, a common STI that impacts 113 million people each year and can result in infertility...
article The frightening emergence of antibiotic-resistant bacteria 17 February 2016 | By Jean-Marie Frere (CIP Universite de Liege), Sebastien Rigali (CIP Universite de Liege) Bacterial resistance to antibiotics is on the rise and a return to the ‘pre-antibiotic’ era has become a frightening possibility. Various factors are responsible for this situation: the overuse of antibiotics in human medicine and animal husbandry, insufficient public funding for research into fundamental bacteriology including resistance mechanisms, and a…
