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Microscopy

news

Tropical frog models reveal novel kidney disease insights

5 November 2021 | By Anna Begley (Drug Target Review)

Scientists utilised CRISPR technology and deep learning systems to investigate the genes associated with polycystic kidney disease.

news

Label-free technique could revolutionise tissue analyses

2 November 2021 | By Anna Begley (Drug Target Review)

A new high-resolution virtual microscopy technique enables the rapid visualisation of tissue, paving the way for histopathology analysis during surgery.

Computer with many medical symbols on screen

news

Groundbreaking data tool may uncover novel class of GPCRs

27 October 2021 | By Anna Begley (Drug Target Review)

A new computer-aided tool maps allosteric sites in G protein-coupled receptors to search for allosteric drugs to treat a range of diseases.

whitepaper

Whitepaper: Phenotypic and functional CAR-T cell characterisation

25 October 2021 | By Sartorius AG

This whitepaper overviews phenotypic and functional characterisation of CAR-T cells with advanced flow cytometry and live-cell analysis.

news

Novel method refines cryogenic electron microscopy (cyro-EM)

21 October 2021 | By Anna Begley (Drug Target Review)

The statistical method known as maximum entropy could improve cryogenic electron microscopy (cryo-EM) for more effective drug treatments.

news

Wyss Centre initiates collaboration to improve brain tumour treatment

13 October 2021 | By Anna Begley (Drug Target Review)

The Wyss Centre has announced a collaborative project to improve understanding of the brain cancer glioblastoma and develop new personalised therapies.

White pills on black surface with COVID-19 structure drawn on

news

Scientists uncover mechanisms of potential COVID-19 drug targets

28 September 2021 | By Anna Begley (Drug Target Review)

Researchers have used CRISPR and cryogenic electron microscopy to unravel the workings of two receptors involved in diseases such as cancer and COVID-19.

news

New precise method can visualise individual blood cells in the brain

31 August 2021 | By Anna Begley (Drug Target Review)

Researchers have developed an inexpensive method for visualising blood flow in the brain that can discern the motions of individual blood cells.

video

On-demand webinar: An AI-based approach to phenotypic characterisation of neuronal cells

26 August 2021 | By Molecular Devices

Evaluation of neurotoxicity effects is an active area of investigation in drug discovery and disease modeling.

whitepaper

Whitepaper: Characterising astroglia models

17 August 2021 | By Sartorius AG

This whitepaper describes several live-cell phenotypic analyses suitable for the characterisation of astroglia cells.

whitepaper

Application note: High-content phenotypic profiling using the cell painting assay

11 August 2021 | By Molecular Devices

The cell painting assay uses up to six fluorescent dyes to label and visualize a variety of subcellular structures at the single cell level.

article

Exclusive report: AI & Informatics: Drug discovery and development

11 August 2021 | By Drug Target Review

In this original report, find an in-depth analysis of AI and informatics within imaging, synthetic biology, drug screening and drug design. Featured interviews with experts from AstraZeneca, Auransa, PolarisQB and Chalmers University of Technology.

Handbook: Latest edition live-cell analysis

whitepaper

Handbook: Latest edition live-cell analysis

10 August 2021 | By Sartorius AG

The latest edition of the live-cell analysis handbook is a companion guide for live-cell analysis users. Includes discussion of live-cell analysis.

news

Thalamus revealed as key area to target for certain brain disorders

2 August 2021 | By Anna Begley (Drug Target Review)

Research shows that cells gather more data inside the thalamus than once believed, potentially changing medicines for brain disorders.

whitepaper

Application note: Measure viral-induced cytopathic effects with a quantitative luminescence assay

28 July 2021 | By Molecular Devices

Depletion of ATP due to viral-induced CPE leads to a reduction in luminescence signal, enabling quantitation of viral-induced CPE in host cells.

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Microscopy