news
Scalable method to image protein levels and changes developed
Using a new CRISPR-Cas9 tagging strategy, researchers have developed a method that enables the imaging of hundreds of proteins in parallel.
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Imaging
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Acquiring structural data on membrane proteins – a spotlight on GPCRs
Lan Zhu from Arizona State University explains how cryo-EM methods can be used to obtain structural information on membrane proteins such as GPCRs.
news
Researchers reveal structure of SARS-CoV-2 Envelope protein
The molecular structure of the SARS-CoV-2 Envelope protein has been identified by researchers using nuclear magnetic resonance.
article
Developing nanobodies and sybodies to combat COVID-19
Three separate studies have identified nanobodies – a miniature form of antibodies found in camelid species – that can bind to the SARS-CoV-2 Spike (S) protein and neutralise the virus in cells.
news
Researchers develop ACE2 decoy to neutralise SARS-CoV-2
Using their de novo protein design strategy, researchers engineered human angiotensin converting enzyme 2 (hACE2) protein decoys that can protect cells from SARS-CoV-2 infection.
news
Lysosomes key to coronavirus shedding, finds study
Scientists reveal that coronaviruses de-activate lysosomes before using them to exit infected cells and spread through the body.
whitepaper
ebook: Phenotypic screening with iPSC-derived cardiomyocytes and neurons
Identify therapeutic effects and adverse responses to compounds earlier in the drug discovery process.
news
New imaging method reveals glycan vaccine targets on HIV molecules
Using cryo-electron microscopy and site-specific mass spectrometry, researchers have mapped the glycans that shield HIV from the immune system.
news
Flow cytometry market to exhibit CAGR of 12 percent
A new report has said that by 2023, the flow cytometry market will be worth $8.88 billion, partly due to an increase in stem cell research.
whitepaper
Webinar: High-content analysis and phenotypic characterisation of 2D and 3D cellular models
Combining 2D and 3D models with live-cell assays allows monitoring of cell responses in real time and provides important insights about compound treatment effects, biological complexity, and physiological relevance of assay results.
whitepaper
Application note: Phenotypic characterisation of neuroactive compound effects
Learn how to perform complex analysis of calcium oscillations and assess cellular and mitochondrial toxicity.
news
Targeting host proteins could lead to pan-coronavirus antivirals
Researchers suggest that targeting host proteins with drugs, rather than directly targeting enzymes or proteins on SARS-CoV-2 and related coronaviruses, could improve outcomes.
whitepaper
Whitepaper: The impact of COVID-19 on neurological systems
Neurological symptoms have been observed in COVID-19 patients. The link between SARS-CoV-2 and the CNS is critical to developing effective treatments
video
Video: Gain deeper insights into cellular 3D structures with water immersion objectives
Water immersion objectives are essential for capturing more data at greater depths in 3D structures, such as spheroids and thick tissues.
whitepaper
Application note: Assess transduction efficiency of CFP-tagged nuclear protein with automated cellular imaging
Evaluating and quantitating nuclear transduction.
