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Kenpaullone protects from cisplatin-induced hearing loss
Researchers have discovered that inhibiting an enzyme called cyclin-dependent kinase 2 protects mice and rats from noise- or drug-induced hearing loss...
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Blocking 20-HETE chemical counters the siren call of aggressive cancers
Scientists have successfully blocked the powerful call of two types of aggressive cancer – glioblastoma and breast cancer – in laboratory models; with evidence that inhibiting the chemical 20-HETE halts tumour growth.
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Drug may curb female infertility from cancer treatments
An existing drug may protect premenopausal women from life-altering infertility that commonly follows cancer treatments...
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First ‘haploid’ human stem cells could change the face of medical research
Research has yielded the first successful isolation and maintenance of haploid embryonic stem cells in humans.
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New cancer drug tested in mice may benefit certain leukaemia patients
Almost 6,000 new cases of acute lymphoblastic leukaemia, or ALL, are expected to be diagnosed this year in the United States. The blood cancer can affect both children and adults.
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Arming T-cells to channel aggression against cancer
Scientists have armed immune cells with a new surface molecule that causes them to respond aggressively when they encounter a protein that tumours actually use to camouflage themselves from the immune system. Researchers from the Helmholtz Zentrum München and various partners introduced the method in ‘Cancer Research’.
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New leukaemia treatment outperforms standard chemotherapies
Researchers at The Australian National University (ANU) are working on a new treatment for an aggressive type of leukaemia that outperforms standard chemotherapies.
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Attacking metastatic tumours in the brain
Targeting HER3 could cripple metastatic cancers that have spread to the brain...
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Blood test offers improved breast cancer detection tool to reduce use of breast biopsy
Study shows 'liquid biopsy' after abnormal mammogram and other imaging can help rule out breast cancer, reduce breast biopsy by up to 67% in women...
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PET/CT helps predict therapy effectiveness in paediatric brain tumours
Brain cancers are difficult to treat, and it can be hard to predict whether a therapy will be effective. When the patient is a child, it's even more important to predict the potential effectiveness of a drug before beginning treatment.
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Antiparasitic drug could be new treatment for brain tumours
New findings could help to extend the lives of patients suffering from one of the most common types of brain tumours - low-grade glioma.
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£100 million for Cancer Research’s ‘grand challenge’ competition winners
Cancer Research UK announced that four international teams are the first recipients of its global £100m Grand Challenge competition, which aims to overcome the biggest challenges facing cancer researchers in a global effort to beat cancer sooner.
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IL-34: a new target to tackle chemo-resistant cancer cells
3 October 2016 | By Niamh Louise Marriott, Digital Content Producer
Researchers found that A549-DR was resistant to the chemotherapeutic drug when transplanted in mice, while A549-DR with depleted IL-34 became sensitive...
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Chemotherapy alternative: research shows Chinese medicine kills cancer cells
8 September 2016 | By Niamh Louise Marriott, Digital Content Producer
Compound kushen injection (CKI) has been used for years in Chinese clinics as an adjunct to western chemotherapy. Researchers used next generation...
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Targeting cancer metabolism
Cancer cells are addicted to glucose and glutamine, which enables them to generate the energy and macromolecule synthesis intermediates to support their growth...
