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Pushpanathan Muthuirulan

Lab Automation In-Depth Focus 2019

In this In-Depth Focus: realising the promise of laboratory automation…

18 March 2019 | By Drug Target Review

In this In-Depth Focus: realising the promise of laboratory automation in biomedical research, drug discovery from the age of information to the age of intelligence, and transforming drug discovery, development and delivery with flow chemistry.

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The changing face in drug discovery

Over the past decade, pharmaceutical industries have contributed enormously to…

1 September 2018 | By Pushpanathan Muthuirulan

Over the past decade, pharmaceutical industries have contributed enormously to the discovery of new innovative drugs that have saved countless human lives. Discovering new drugs is a complex team sport that requires an intellectual collaboration across many sectors. These advancements provide powerful tools that arm scientists in the quest for…

Pushpanathan Muthuirulan Harvard University, Cambridge

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Pushpanathan Muthuirulan

Research Associate, Harvard University

13 August 2018 | By

Research Associate, Harvard University

article

Lab Automation In-Depth Focus 2018

In this issue: how lab automation has accelerated pharmaceutical research…

16 March 2018 | By Drug Target Review

In this issue: how lab automation has accelerated pharmaceutical research by simplifying operations, reducing manual tasks and increasing the efficiency, quality and reproducibility of results.

article

Flow cytometry – accelerating neuroscience research

Flow cytometry continues to evolve at a fast pace and…

18 September 2017 | By Pushpanathan Muthuirulan

Flow cytometry continues to evolve at a fast pace and provides neuroscientists with the ability to perform many highly-specialised assays simultaneously. It meets the demands of cutting-edge research in neuroscience that has allowed researchers to isolate particular neural cells from heterogeneous population and catalogue its molecular or physical features...

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NGS: empowering infectious disease research beyond reality

Pushpanathan Muthuirulan & Pooja Sharma explain how high-throughput next-generation sequencing…

13 September 2017 | By Pooja Sharma, Pushpanathan Muthuirulan

Pushpanathan Muthuirulan & Pooja Sharma explain how high-throughput next-generation sequencing (NGS) technologies are revolutionising our ability to characterise infectious diseases at genomic, transcriptomic and epigenetic levels...

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NGS In-Depth Focus 2017

Next-generation sequencing is a crucial part of the scientist's toolkit.…

12 September 2017 | By Drug Target Review

Next-generation sequencing is a crucial part of the scientist's toolkit. This in-depth focus compares the strengths and weaknesses of a range of NGS technologies and examines the benefits and challenges of using it in infectious disease diagnosis...

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Drug Target Review – Issue #3 2017

Included in this issue: The importance of industry partnerships; Calcilytics…

6 September 2017 | By Drug Target Review

Included in this issue: The importance of industry partnerships; Calcilytics as potential novel therapeutic treatments to halt Alzheimer's disease; Accelerating neuroscience research with flow cytometry...

Next-Generation Sequencing In-Depth Focus 2016

article

Next-Generation Sequencing In-Depth Focus 2016

NGS technologies have been employed in a wide range of…

11 December 2016 | By Michael W. Pfaffl, Pushpanathan Muthuirulan

NGS technologies have been employed in a wide range of areas in drug discovery, including drug target identification, biomarker discovery and biopharmaceutics development. Pushpanathan Muthuirulan of the National Institutes of Health gives us an overview of this in his article in our NGS In-Depth Focus. Meanwhile, the possibilities that RNA-Seq…

article

Flow cytometry: breaking bottlenecks in drug discovery and development

The discovery and development of novel drug candidates is a…

20 September 2016 | By Pooja Sharma, Pushpanathan Muthuirulan

The discovery and development of novel drug candidates is a highly complex, time-consuming and expensive process. Pharmaceutical scientists and clinicians should, therefore, reevaluate and modify the existing standard platforms and increase their uptake of robust advanced technologies such as flow cytometry to overcome the bottlenecks in these processes...

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Pushpanathan Muthuirulan