news NPSR1 gene discovered as a key cause of endometriosis 31 August 2021 | By Anna Begley (Drug Target Review) NPSR1 has been identified as a genetic cause of endometriosis, revealing a potential drug target that may lead to better therapies.
news Radiopharmaceuticals and nanoparticles used to kill cancer cells 15 June 2021 | By Victoria Rees (Drug Target Review) Researchers have developed a potential cancer treatment using light from radiopharmaceuticals and polymer nanoparticles to kill cancer cells.
news Team uses antibodies to tag disease-related proteins for destruction 19 March 2021 | By Victoria Rees (Drug Target Review) Researchers have developed a technique utilising antibodies to tag disease-causing proteins, to treat the underlying causes of disease.
news Over 200 molecules and genes linked to COVID-19 severity 14 October 2020 | By Victoria Rees (Drug Target Review) A team has identified 219 molecules and genes that influence the severity of COVID-19 in patients, providing information that could aid the development of therapeutics.
news Researchers identify potential drug target for depression in primates 15 August 2019 | By Nic Losardo (Drug Target Review) A study has discovered a molecule key in neuronal growth that could be used as a drug target to treat anxiety-related diseases.
news Study suggests immune cells play vital role in fungal disease 1 July 2019 | By Victoria Rees (Drug Target Review) New research has revealed the immune cells may be critical in moving pathogenic fungal spores to the central nervous system, pointing to drug target.
news Efficacy of breast cancer therapy measured using PET imaging 12 February 2019 | By Iqra Farooq (Drug Target Review) Researchers have developed a method using PET imaging along with 18F-fluorofuranylnorprogesterone to analyse the efficacy of breast cancer treatments...
news CRISPR repurposed to develop better antibiotics 14 January 2019 | By Iqra Farooq (Drug Target Review) Mobile-CRISPRi could be used to guide gene expression, in turn control levels of proteins produced, enabling scientists to identify key antibiotic targets...
news Insights into controlling gene expression 9 January 2019 | By Iqra Farooq (Drug Target Review) A study has given insight into gene expression and could enable scientists to determine how certain RNAP inhibitors work within the body...
news GFAP gene mutation creates tangles in brain cells – cause of neurological disease 26 October 2018 | By Drug Target Review A recent study in the U.S. has identified how a mutation in the GFAP gene, which encodes for the GFAP protein, causes the tangles in brain cells associated with Alexander disease and may also impact other neurological diseases.
news Clearest image of Ebola virus protein gained by researchers 18 October 2018 | By Drug Target Review Researchers collaborated to identify the clearest image of the Ebola virus protein ever obtained using a cryo-electron microscope...
news Bacterial outer membranes may be key to new antibiotics 22 July 2018 | By Drug Target Review The outer membrane surrounding the cell wall of bacteria may be a key target for approaches to a new form of antibacterial drugs...
news Researchers uncover new target to stop cancer growth 22 June 2018 | By Drug Target Review Researchers have discovered that a protein called Munc13-4 helps cancer cells secrete large numbers of exosomes that stimulate tumour progression...
news Tracking changes in circulating tumour cells shows promise for cancer screening 19 March 2018 | By Drug Target Review Researchers in the United States have developed improved methods for capturing circulating tumour cells (CTCs) on clinical samples, with a view to assessing treatment for cancer patients and screening for the disease.
news Cell transplant that responds to designer drugs treats Parkinson’s disease 28 April 2016 | By Victoria White, Digital Content Producer Su-Chun Zhang created two related cell types. When the cells detect the designer drug, one type ramps up production of dopamine; the other chokes it off...