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Largest psoriasis meta-analysis to date yields new genetic clues

24 May 2017 | By Niamh Marriott (Drug Target Review)

1-2% of the US population have psoriasis, an immune-mediated disease that causes red, patchy and scaly marks on the skin.

Blood test offers improved breast cancer detection tool to reduce use of breast biopsy

24 May 2017 | By Niamh Marriott (Drug Target Review)

Study shows 'liquid biopsy' after abnormal mammogram and other imaging can help rule out breast cancer, reduce breast biopsy by up to 67% in women...

Cancer drug proves effective against common allergies

23 May 2017 | By Northwestern University

A cancer drug for patients with certain types of leukaemia and lymphoma can also prevent reactions to some of the most common airborne allergens, according to a recent Northwestern Medicine study. The promising data from this pilot study could have greater implications for adults with food allergies.

Protective responses appear weaker in neural stem cells from Huntington disease patients

Protective responses appear weaker in neural stem cells from HD patients

23 May 2017 | By Sarah Wills (Drug Target Review)

A multi-institutional team based at Massachusetts General Hospital (MGH) has discovered how a potential treatment strategy for Huntington disease (HD) produces its effects, verified its action in human cells and identified a previously unknown deficit in neural stem cells from patients with HD.

The fungal microbiome contributes to alcohol-induced liver damage in mice

23 May 2017 | By Niamh Marriott (Drug Target Review)

Alcoholism contributes to nearly half of liver cirrhosis-related deaths in the United States.

Antibodies as ‘messengers’ in the nervous system

22 May 2017 | By Niamh Marriott (Drug Target Review)

Antibodies are able to activate human nerve cells within milliseconds and hence modify their function.

Researchers discover neural stem cells that can become blood vessels

22 May 2017 | By Niamh Marriott (Drug Target Review)

This finding could have a great impact on the study of paediatric tumours, as it could already constitute one of the factors that produces their growth.

DFG €66 million funding for 15 new research training groups

22 May 2017 | By Niamh Marriott (Drug Target Review)

The Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) is establishing 15 new Research Training Groups to further support early research...

Scientists to test Zika virus on brain tumours

19 May 2017 | By Niamh Marriott (Drug Target Review)

The research, using tumour cells in the laboratory and in mice, will see if the Zika virus can destroy cancer cells.

Wildlife conservation plans must consider Lyme disease risk

19 May 2017 | By Niamh Marriott (Drug Target Review)

Lyme disease – an infection contracted from the bite of an infected tick– is an important emerging disease in the UK, and is increasing in incidence in people in the UK and large parts of Europe and North America.

Skin cancer on the rise – diagnosis of two types has increased

19 May 2017 | By Niamh Marriott (Drug Target Review)

New diagnoses for two types of skin cancer increased in recent years, according to a Mayo Clinic-led team of researchers.

Spread of tau protein measured in the brains of Alzheimer’s patients

18 May 2017 | By Niamh Marriott (Drug Target Review)

In a new study researchers measured how deposits of the pathological protein tau spread through the brain over the course of Alzheimer’s disease.

Preclinical candidate CGRP antagonist selected for advancement as potential migraine treatment

Preclinical candidate CGRP antagonist has potential as treatment for migraines

18 May 2017 | By Sarah Wills (Drug Target Review)

A preclinical candidate calcitonin gene-related peptide (CGRP) antagonist has been nominated for advancement into further preclinical studies as an investigational treatment for migraine.

Control mechanism unveiled for gene that causes Opitz syndrome

18 May 2017 | By Niamh Marriott (Drug Target Review)

Opitz G/BBB (Opitz) syndrome is a hereditary disorder that affects people in different ways, causing malformations in medial (midline) organs and structures, intellectual disability and developmental disorders.

Anticancer nanomaterials created by simulating underwater volcanoes

17 May 2017 | By Niamh Marriott (Drug Target Review)

Researchers at Aalto University, Finland, have developed anticancer nanomaterials by simulating the volcano-induced dynamic chemistry of the deep ocean.

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