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Osteoporosis

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Genetic profile of skeleton osteocytes mapped for first time

6 May 2021 | By Victoria Rees (Drug Target Review)

Researchers have revealed which genes are switched on or off in osteocytes, a bone cell found in the skeleton.

cartoon of two hips and femurs - left on with large black dots in the bone indicating osteoporosis (bone being removed and becoming spongy), the other with smaller dots indicating normal bone

news

MALP cells as a potential target for osteoporosis drug development

23 November 2020 | By Hannah Balfour (Drug Target Review)

Researchers have found that bone marrow adipogenic lineage precursor (MALP) cells may initiate the production of osteoclasts and drive bone remodelling in osteoporosis.

news

Novel biomaterial could be used to accelerate bone regeneration

15 June 2020 | By Victoria Rees (Drug Target Review)

In lab conditions, a new biomaterial was able to accelerate bone regeneration by boosting an immune response that encourages repair.

article

The growing possibilities for stem cells in pharma

28 January 2020 | By Hannah Balfour (Drug Target Review)

Drug Target Review explores the latest applications of stem cells in modelling disease, drug production and the most recent steps in regenerative medicine provided by research.

news

Activating bone stem cells has potential therapeutic applications

10 December 2019 | By Victoria Rees (Drug Target Review)

A study has demonstrated that activating bone periosteal stem cells leads to increased bone healing in mice, presenting a potential therapeutic strategy.

news

Osteoporosis in mice reversed with new drug target

21 August 2019 | By Rachael Harper (Drug Target Review)

A pharmaceutical target has been identified by Duke University that, when activated, can reverse bone degradation caused by osteoporosis.

news

Small molecule factors found to influence age-related bone deterioration

18 September 2018 | By Drug Target Review

Scientists in the U.S. have reported findings about the mechanisms that contribute to the experience of weaker bones with age.

news

Removing old cells could extend joint health & stop osteoarthritis

27 April 2017 | By Niamh Marriott (Drug Target Review)

In a preclinical study in mice and human cells, researchers report that selectively removing old or 'senescent' cells from joints could stop and even reverse the progression of osteoarthritis.

news

Regenerating bone and cartilage tissues from apple waste

3 April 2017 | By Niamh Marriott (Drug Target Review)

Researchers from UPM and CSIC have employed waste from the agri-food industry to develop biomaterials that are able to act as matrices to regenerate bone and cartilage tissues, which is of great interest for the treatment of diseases related to ageing.

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Osteoporosis