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Canadian researchers have identified several unknown chemicals that were consistently associated with babies who had cystic fibrosis (CF), including two different drug and environmental compounds the infants secreted in sweat at much lower concentration levels...
Couples who are undergoing pre-implantation genetic diagnosis (PGD) in order to avoid transmission of inherited diseases, such as Duchenne muscular dystrophy or cystic fibrosis, should also have their embryos screened for abnormal numbers of chromosomes at the same time, say Italian researchers.
A new study has found that stem cell therapy can reduce lung inflammation in an animal model of chronic obstructive pulmonary disease (COPD) and cystic fibrosis. Although, still at a pre-clinical stage, these findings have important potential implications for the future treatment of patients.
Sound Pharmaceuticals has been awarded up to $1.6M from Cystic Fibrosis Foundation Therapeutics (CFFT), the non-profit drug discovery and development affiliate of the Cystic Fibrosis Foundation.
Despite that over 1,900 mutations of the cystic fibrosis transmembrane conductance regulator cause cystic fibrosis, only two treatment options exist.
In this Personalised Medicines In-Depth Focus, Dr Adrian Harel talks about the importance of developing a diagnostic test and better treatments for traumatic brain injury. Plus, Caroline Richards, Editor of Drug Target Review explores the need for mutation specific treatments in cystic fibrosis...
22 July 2016 | By Victoria White, Digital Content Producer
Drug Target Review recently caught up with Lorence Kim, Chief Financial Officer of Moderna, to find out more about the company‘s collaboration with Vertex and using mRNA therapeutics to treat patients with cystic fibrosis...
6 July 2016 | By Victoria White, Digital Content Producer
Their collaboration will focus on the use of mRNA therapies to enable cells in the lungs to produce functional copies of the CFTR protein...
9 June 2016 | By Victoria White, Digital Content Producer
Researchers have identified new molecules that could help in the fight to prevent diseases caused by faulty ion channels, such as cystic fibrosis...
13 January 2016 | By Victoria White
Researchers have discovered that the XBP-1 pathway was implicated in the hyper-inflammatory response of cystic fibrosis alveolar macrophages...
30 November 2015 | By Victoria White
By removing these interactions, the researchers partially restored the protein’s normal function. The findings suggest that therapies could one day treat the root cause of cystic fibrosis, not just the symptoms...
16 November 2015 | By Victoria White
Scientists have reported an improved gene therapy treatment can cure mice with cystic fibrosis. Cell cultures also responded well to the treatment...
26 October 2015 | By Victoria White
The collaboration will evaluate the use of CRISPR-Cas9 across multiple diseases, including cystic fibrosis, where targets have been validated through human genetics...
7 September 2015 | By Victoria White
Basilea is to work with the iABC consortium to develop an inhaled formulation of its antibiotic BAL30072 as part of a new Europe-wide programme...
2 September 2015 | By Victoria White
ESCMID advocates the need for greater education, guidance and research on the build-up, treatment and prevention of biofilms...
