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Computational model identifies new candidate cancer genes
A novel computational method has led to the discovery of genes whose alteration may contribute to cancer susceptibility and may lead to new therapeutic targets for cancers.
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Breast cancer
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Making tumour cells stiff could prevent cancer metastasis
A study has demonstrated that the stiffness of cells indicates whether a tumour will spread and inducing this state could help to avoid metastasis.
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Molecule discovered that regulates development of tumours
Researchers discover that a non-coding region of the genome originates a key molecule for the proliferation of cancerous tumours.
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Breast cancer ‘sleeper cells’ could be formed after drug treatment
Breast cancer medicines may force some cancer cells into 'sleeper mode', allowing them to potentially come back to life after treatment.
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Blocking kinase could provide treatment for prostate cancer
Researchers have found that inhibiting a kinase in mice leads to the death of prostate cancer cells, providing a potential therapeutic target.
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Immune cell function in cancer immunotherapy revealed
Researchers have discovered the roles that immune cells play in tumour growth and breast cancer immunotherapy which could aid in drug development.
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Interferon pathway could provide drug target for cancers
A study has found that signals from interferons can be blocked, allowing the immune system to attack tumours which provides a potential target.
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Discovering new routes to cancer drug discovery with neutrons
From the world’s flagship neutron science facility, Institut Laue-Langevin (ILL), Matthew Blakeley shares insights into how they are harnessing the power of neutrons to aid their search for new cancer treatments.
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Method for radiolabelling antibodies against breast cancer developed
Researchers from the University of Zurich have created a new method for radiolabelling antibodies using UV light - with proteins being ready-to-use for cancer imaging or therapy in less than 15 minutes.
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Efficacy of breast cancer therapy measured using PET imaging
Researchers have developed a method using PET imaging along with 18F-fluorofuranylnorprogesterone to analyse the efficacy of breast cancer treatments...
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The path of metallodrugs in breast cancer cells
The path a metallodrug uses to target and kill cancer cells could be used to design drugs to target triple-negative breast cancer...
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A high-throughput approach for measuring intracellular ATP levels to access compound-mediated cellular toxicity
Many drugs fail in clinical trials due to toxicity-related issues; therefore, drug-mediated cellular toxicity should be determined at an early stage in the drug discovery value chain. There are many assay systems that can be utilised to measure cellular toxicity. In this article we demonstrate that intracellular ATP concentrations are…
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Cryoablation could treat low risk breast cancer
A study by Princeton Radiology researchers has found that cryoablation could be effective in targeting low risk breast cancer...
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Breast cancer recruits cells from bone marrow to boost growth
A study has shown that breast cancer uses stromal cells originally formed in bone marrow to boost their growth and metastasis of the cancer...
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Paclitaxel acting as an immune response modulator
Brazilian researchers have discovered that a drug widely used as for chemotherapy also acts as an immune response modulator...
