Application note: Analysis of Inflammatory Plasma Biomarkers in Cancer Patient Samples
The Simoa CorPlex Human Cytokine Panel 1 is a multiplex immunoassay for the quantitative measurement of 10 inflammatory biomarkers in serum and EDTA plasma.
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Whitepapers
Application note: Assess cell viability and proliferation with colorimetric readouts
MTT and Cell Cytotoxicity assay kits from Abcam can both be used to measure cell proliferation (viable cells) and cytotoxicity. The choice of which assay to use is mainly based on the desired workflow and time required to complete an assay.
Application note: Reliable Single Cell Cloning with Advanced Microfluidic Dispensing
Find out how to accelerate and improve selective single cell cloning with advanced microfluidic dispensing.
Application note: Streamline BCA-based protein quantitation on the SpectraMax iD5 reader
Learn how to quantitate a cellular protein sample with BCA protein assay kits on the SpectraMax® iD5 Multi-Mode Microplate Reader from Molecular Devices.
eBook: Capture True 3D Cell Culture Insights
Developing more complex, biologically relevant, and predictive cell-based assays for compound screening is a primary challenge in drug discovery.
Application note: Evaluate anti-inflammatory compounds using a multiparametric THP-1 cell-based assay
Macrophages originate from blood monocytes that leave the circulation and penetrate various tissues where they differentiate into macrophages. They are involved in the removal of pathogens and phagocytosis of dead cells. In addition, they initiate inflammation by releasing cytokines that activate vascular cells and facilitate macrophage adhesion to blood vessels…
Application note: Explore cardiac function by measuring calcium oscillation or contraction patterns
Understanding the impact of drugs on the cardiac system early in the development process is critical to improving the safety of drugs getting to market.
Application note: Automated imaging of cell viability
Automated fluorescence imaging and quantification of cell viability, with EVOS cell imaging system
Guide: Immunology basics
A global general immunology guide delivering the fundamentals of innate and adaptive immunity, including the description of immune cell types and their associated signaling pathways
Application note: High-throughput imaging and analysis of spheroids
High-throughput fluorescence imaging and analysis of spheroids - tips, tricks, and tools to efficiently grow, stain, image, and analyze 3D cell cultures
eBook: Explore pathways like a pro
Scientists studying particular disease states often search cellular signaling pathways to gain insight into DNA, RNA, and protein function.
eBook: Quantitate Neuron Potential
Gain valuable insights for interpreting neurobiology, from evaluation of ion channels to analysis of 3D neuron organoids.
Whitepaper: Evaluating the impact of error rate on productivity and cost savings in synthetic DNA fragments
GeneArt High-Q Strings DNA Fragments versus other suppliers’ products.
Application note: Cell line development: accelerating antibody discovery by monitoring titre and glycosylation with the Octet® platform
Cell line development typically includes the screening of thousands of clones to identify the few that are stable, grow as expected and produce high yields of the bioproduct.
Application note: Multiplexed automated imaging assay for cardiotoxic compounds using the ImageXpress Pico system
There is an increasing need to expand the variety and complexity of cell-based assays for biologic research and drug discovery.