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Vaccine

Drug Target Review Vaccine Development ebook 2021

22 September 2021 | By Drug Target Review

Within this ebook, find articles examining the role of telomerase for universal cancer vaccines and discussing potential targets for neurodegenerative disease vaccines.

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Drug Target Review – Issue 3 2021

22 September 2021 | By Drug Target Review

In this issue, find articles exploring why CRISPR is useful for high-throughput drug discovery, how targeting telomerase may lead to universal cancer vaccines and a new study to identify therapeutics that can be repurposed against COVID-19. Also included are features on neuroscience, organoids and antibodies.

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MEPs demand action plan to end animal testing in Europe

16 September 2021 | By Anna Begley (Drug Target Review)

MEPs have requested that the EU adopts new plans to phase out the use of animals in scientific research and testing, focusing on alternatives instead.

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Study suggests how to develop intranasal vaccines for COVID-19 and flu

30 August 2021 | By Anna Begley (Drug Target Review)

New research has explored the role of nasal bacteria to better develop intranasal vaccines for viruses such as COVID-19 and flu.

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Spike gene mutants could be used as novel COVID-19 vaccine

27 August 2021 | By Anna Begley (Drug Target Review)

SARS-CoV-2 Spike gene mutants may be developed into immunogens for new vaccines against COVID-19, a study in hamsters has shown.

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Intranasal COVID-19 vaccine shown to be effective in animal models

26 August 2021 | By Anna Begley (Drug Target Review)

A nasal spray of the COVID-19 Vaccine Oxford/AstraZeneca was found to protect hamsters and monkeys against SARS-CoV-2 in an NIH study.

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Scientists develop novel strategy for tuberculosis vaccine

25 August 2021 | By Anna Begley (Drug Target Review)

A research team have created a new strategy for developing an effective vaccine against a widespread form of tuberculosis.

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CureVac and GSK COVID-19 vaccine shows promise in pre-clinical study

17 August 2021 | By Anna Begley (Drug Target Review)

CureVac and GSK's second-generation mRNA COVID-19 vaccine candidate, CV2CoV, demonstrated improved immune response in a pre-clinical study.

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Artificial intelligence may reveal how microbiome affects vaccine response

6 August 2021 | By Anna Begley (Drug Target Review)

Researchers have been using artificial intelligence to study how the microbiome interacts with the human system to improve vaccine response.

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Masitinib found to be an effective COVID-19 treatment in mouse model

3 August 2021 | By Anna Begley (Drug Target Review)

Scientists from the University of Chicago discovered that the drug masitinib inhibits the replication of SARS-CoV-2 in mice.

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New “atlas” charts how antibodies attack COVID-19 Spike variants

26 July 2021 | By Anna Begley (Drug Target Review)

A new “atlas” has been created in the US that charts how 152 different antibodies attack the SARS-CoV-2 Spike protein.

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Newly designed tumour vaccine could prevent cancer recurrence

9 July 2021 | By Anna Begley (Drug Target Review)

Scientists have used nanotechnology to develop personalised tumour vaccines which prevented cancer recurrence and metastasis challenges in mouse models.

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Anticoagulant drug a possible strategy to treat COVID-19 variants

8 July 2021 | By Anna Begley (Drug Target Review)

Researchers in Australia have discovered a new site on the COVID-19 Spike protein that could be targeted by an anticoagulant drug.

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Metabolic pathway could potentially enhance vaccine effectiveness

8 July 2021 | By Anna Begley (Drug Target Review)

A metabolic control pathway that regulates T follicular helper cells could enhance vaccine effectiveness, including those that protect against COVID-19.

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Novel vaccine against coronaviruses protects mice from infection

23 June 2021 | By Victoria Rees (Drug Target Review)

A new mRNA-based vaccine has demonstrated success at protecting against multiple coronaviruses in pre-clinical studies.

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Vaccine