The newly developed chip includes heart and breast cancer tissues and could be used to predict the cardiac toxicity of chemotherapeutic drugs.
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Identify therapeutic effects and adverse responses to compounds earlier in the drug discovery process.
Combining 2D and 3D models with live-cell assays allows monitoring of cell responses in real time and provides important insights about compound treatment effects, biological complexity, and physiological relevance of assay results.
Learn how to perform complex analysis of calcium oscillations and assess cellular and mitochondrial toxicity.
Water immersion objectives are essential for capturing more data at greater depths in 3D structures, such as spheroids and thick tissues.
There has been growing interest in using high-content imaging methods for studying mitochondria.
A natural pigment from Monascus purpureus can be used to stain cells and distinguish between live and dead ones in toxicology studies.
Many anti-angiogenic drugs have been developed to use in cancer therapy, while pro-angiogenic molecules may hold potential in regenerative applications.
A powerful, yet affordable, high-content imaging system in your own lab.
Following their success in organoid systems, two drug candidates are now to be administered to ferrets and tested against COVID-19.