List view / Grid view
Target Validation
webinar
High throughput flow cytometry for multifactorial evaluation of novel therapeutic candidates using an innovative In vitro immuno-oncology screening platform
4 January 2018 | By IntelliCyt Corporation
In this webinar, speakers discussed how the IntelliCyt iQue Screener Plus platform is being utilised to deliver rich datasets for compound screening, target validation and is how it is transforming immuno-oncology.
whitepaper
Scientific poster: Developing protein: Protein Interaction (PPI) assays with AlphaLISA and LANCE TR-FRET
In this scientific poster, PerkinElmer demonstrates the ease and utility of using AlphaLISA® and LANCE® TR-FRET homogenous assay forms for studying PPIs.
article
Using bioinformatics sequence similarities to optimise repurposing activities
A significant amount of selectivity and potency data originating from screening of drug targets is generated each year and deposited in public databases. This can be exploited to accelerate drug discovery, in particular, for a variety of repurposing activities...
article
Q&A: Integrated drug discovery panel – your questions answered
Drug discovery from concept to drug candidate has become a collective effort where multi-disciplinary project teams from CROs work with drug companies and academia to deliver clinical candidates, overcoming multi-factorial research obstacles along the way.
news
Sonic Hedgehog pathway identified as a target against medulloblastoma
Researchers raise hopes for developing a combination targeted therapy to treat medulloblastoma and other tumours...
webinar
Integrated drug discovery panel – your questions answered!
28 September 2017 | By Charles River
During this peer panel discussion, team members from Charles River discussed their views and strategies on Drug Discovery...
webinar
Webinar: Phenotypic assays for CNS disease drug discovery
21 September 2017 | By Charles River Laboratories
In this webinar, we highlight in vitro models and phenotypic assays to discover and validate novel targets and promising lead molecules...
news
£8500 given to cancer research at the University of Warwick
Cancer research at the University of Warwick has received a boost thanks to the former Lord Mayor of Coventry Cllr Lindsley Harvard.
article
Intracellular target validation in cellular systems … using peptides!
Paul Grant from Venomtech suggests that because animal venoms contain proteins and peptides that disrupt cell membrane integrity, they offer a new approach to drug discovery...
news
Blood cell discovery identifies patients with aggressive prostate cancer
Patients who have aggressive prostate cancer could be identified by a highly accurate and simple blood test, according to a new study.
news
Balance and movement improved in animal model of Parkinson’s disease
Researchers have developed a molecular compound that improves balance and coordination in mice with early stage Parkinson's disease.
news
New leukaemia treatment outperforms standard chemotherapies
Researchers at The Australian National University (ANU) are working on a new treatment for an aggressive type of leukaemia that outperforms standard chemotherapies.
news
Diabetes drug prevents cardiovascular disease in obese mouse study
A study by researchers at the University of Missouri School of Medicine found that the diabetes medication linagliptin can protect against stiffening of the left ventricle of the heart in overweight female mice. The finding may have implications for management of cardiovascular disease in humans.
article
Targets In-Depth Focus 2017
Included in this Targets In-Depth Focus: Intracellular target validation in cellular systems; New drug targets identified to defend against chlamydia infections using CRISPR and stem cells; Novel solutions for tough targets with real bite...
