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Blood cell discovery identifies patients with aggressive prostate cancer
Patients who have aggressive prostate cancer could be identified by a highly accurate and simple blood test, according to a new study.
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Stem Cells
Stem cells are undifferentiated biological cells that can differentiate into specialised cells and can divide to produce more stem cells.
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Cells change type to help or hinder immunity
Scientists have discovered a mechanism that provides a possible new target for allergy treatments, which may bring hope for asthma sufferers.
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Stem Cells In-Depth Focus 2017
Included in this Stem Cells In-Depth Focus: Translating discoveries into therapies; The key to successful manufacturing of patient-specific cell therapies; Interview with Alessandro Prigione and James Adjaye...
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Insights from discovery through clinical efficacy to support a new class of therapeutics in Alzheimer’s disease
Research into innovative small molecule therapeutics with disease modifying potential in Alzheimer’s disease (AD) has been conducted at Alzheon since 2013.
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Scientists give tumour-fighting cells a boost in battling bone marrow cancer
Researchers uncovered a new way to enhance the function of a specific type of immune cell that destroys tumours in multiple myeloma...
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Drug Target Review – Issue #2 2017
Included in this issue: Technology convergence improves testing; Screening; Stem Cells; Targets; Mass Spectrometry; and Therapeutics in Alzheimer's disease...
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The immune system promotes spontaneous heart regeneration
In adult mammal hearts, cardiomyoctyes do not proliferate following damage, like that caused by myocardial infarction.
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Healing wounds with cell therapy
An experimental treatment in mice allows the reprogramming of blood cells in order to promote the healing process of cutaneous wounds...
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Faulty immune cells may play role in alopecia and baldness
The new study suggests that defects in Tregs could be responsible for alopecia areata, a common autoimmune disorder that causes hair loss, and could potentially play a role in other forms of baldness, including male pattern baldness
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Cancer drug proves effective against common allergies
A cancer drug for patients with certain types of leukaemia and lymphoma can also prevent reactions to some of the most common airborne allergens, according to a recent Northwestern Medicine study. The promising data from this pilot study could have greater implications for adults with food allergies.
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Protective responses appear weaker in neural stem cells from HD patients
A multi-institutional team based at Massachusetts General Hospital (MGH) has discovered how a potential treatment strategy for Huntington disease (HD) produces its effects, verified its action in human cells and identified a previously unknown deficit in neural stem cells from patients with HD.
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Researchers discover neural stem cells that can become blood vessels
This finding could have a great impact on the study of paediatric tumours, as it could already constitute one of the factors that produces their growth.
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Scientists to test Zika virus on brain tumours
The research, using tumour cells in the laboratory and in mice, will see if the Zika virus can destroy cancer cells.
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New gene variant identified in ALS provides treatment hope
A new study shows that a variant in UBQLN4 gene has been associated with Lou Gehrig's disease, or amyotrophic lateral sclerosis (ALS). The study also describes how this gene variant disrupts a cellular process that drives motor neuron development. This new insight opens the door to potential treatment targets for…
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Using single-cell RNA sequencing to track stem cell development
Adult stem cells have the ability to transform into many types of cells, but tracing the path individual stem cells follow as they mature and identifying the molecules that trigger these fateful decisions are difficult in a living animal.
