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Stem Cells

Stem cells are undifferentiated biological cells that can differentiate into specialised cells and can divide to produce more stem cells.

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ISSCR 2018 to highlight research driving new discoveries and advances in regenerative medicine

8 June 2018 | By ISSCR

Progress in stem cell research and its translation to medicine is the focus of the International Society for Stem Cell Research annual meeting 20-23 June at the Melbourne Convention & Exhibition Centre in Melbourne, Australia.

article

Automated assessment of liver and cardiac toxicities in lead optimisation

8 June 2018 | By Tecan

This webinar, supported by Tecan, focused on the automated assessment of liver and cardiac toxicities in lead optimisation, using biochemical and human iPS cell assays.

Liz Quinn, Associate Director, Stem Cell Marketing, Takara Bio USA

article

Expert view: Overcoming the problems of working with human primary hepatocytes

7 June 2018 | By Liz Quinn (Associate Director - Stem Cells Marketing at Takara Bio USA)

Human primary hepatocytes (hpheps) are the gold standard for in vitro evaluation of drug metabolism, drug-drug interactions, and metabolic disease research. However, hpheps don’t survive in standard 2D culture for very long – no longer than two or three days.

whitepaper

Application note: Cellartis® Power™ Primary HEP Medium – extend functionality of your primary hepatocytes to 4 weeks

7 June 2018 | By Takara Bio

Human primary hepatocytes (hphep cells) are the gold standard for in vitro evaluation of drug metabolism, drug-drug interactions, safety assessment of drug candidates, and disease modeling.

article

The role of biomaterials in stem cell-based regenerative medicine

6 June 2018 | By Laura Goldie - Head of Technical Services - Biogelx Ltd.

Despite their vast therapeutic potential in such areas as cell therapy and tissue engineering, stem cells have yet to live up to their original hype and demonstrate widespread clinical success.

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Blood stem cells balance the immune system by teamwork

4 June 2018 | By Drug Target Review

The human body’s blood stem cells produce approximately 10 billion new white blood cells – termed immune cells – every day. Scientists in the U.S. have now discovered that some blood stem cells pick up the slack should any others fail to achieve these levels.

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Stem Cells In-Depth Focus 2018

31 May 2018 | By Drug Target Review

In this issue: urine-derived stem cells offer an innovative platform for drug testing and disease modelling, a paradigm shift in translational stem cell research, and the role of biomaterials in stem cell-based regenerative medicine.

Issue 2 2018 Drug Target Review magazine

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Drug Target Review – Issue #2 2018

31 May 2018 | By Drug Target Review

In this issue: the positive impact of genomics on drug discovery, development and deployment, the confluence of biology and technology, and Artificial Intelligence: harnessing the potential to drive progress in drug discovery promises much for phenotypic drug discovery

news

Macrophages support mammary stem cells via chemical signalling

21 May 2018 | By Drug Target Review

An international team of scientists has discovered that one of the biggest hitters in the immune system, macrophages, provide a cradle for mammary stem cells...

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Elastic microspheres expand understanding of embryonic development and cancer cells

15 May 2018 | By Drug Target Review

A new technique that uses tiny elastic balls filled with fluorescent nanoparticles aims to expand the understanding of the mechanical forces that exist between cells...

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Scientists overcome cell rejection in neuron replacement treatment for spinal cord injuries

11 May 2018 | By Drug Target Review

Scientists have successfully overcome the persistent cell rejection that has hitherto plagued attempts to introduce neural stem cells to replace damaged tissue in pigs.

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Cellular reprogramming promotes muscle regeneration in injured mice

9 May 2018 | By Drug Target Review

Scientists have developed a simple and robust approach for directly reprogramming mature skin cells into immature muscle cells...

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Scientists study long-term effects of stem cell treatment for AICLI

4 May 2018 | By Drug Target Review

Researchers in China have conducted a unique study investigating the long-term effects of stem cells to treat angiitis-induced critical limb ischemia (AICLI).

whitepaper

Whitepaper: Smart cell monitoring

3 May 2018 | By Del Trezise, Essen BioScience

This whitepaper outlines how advances in real-time live-cell monitoring and analysis methods are addressing these changing needs.

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ALS researchers begin recreating human spinal cords on a chip

30 April 2018 | By Dr Zara Kassam (Drug Target Review)

NIH-funded study closes in on personalised drug testing for neurological disorders...

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Stem Cells