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Experimental mAb subdues type 1 diabetes in laboratory mice
A monoclonal antibody given to mice reversed type 1 diabetes by suppressing the actions of glucagon, a study has shown.
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Pharmacology
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NAD depletion by IFN sensitises pancreatic cancer to NAMPT inhibition, study shows
High IFN signalling in pancreatic tumours are sensitive to NAMPT inhibitors which block a pathway in NAD synthesis, presenting a drug target.
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Novel enterocyte-like cells developed by researchers from stem cells
A team has developed enterocyte-like cells from hiPSCs, which can be used to study the absorption of novel oral drugs.
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Safer and more affordable medicine for all? How pharmacogenomics may level the playing field
Dr Mike Tocci discusses how pharmacogenomics can revolutionise medical research and improve the efficacy and quality of drugs.
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Progression, trends and industry leaders in HIV and AIDS research
HIV is a disease still common in sub-Saharan Africa despite global research since 1982. This article delves into the trends, opportunities and key players in HIV research, exploring future possibilities for treating the disease.
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PJ34 triggers self-destruction of human pancreatic cancer cells
A study conducted on human pancreatic tumours transplanted in mice reveals promise for an effective therapy in the future, say researchers.
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How receptors for medicines work inside cells
G protein-coupled receptors are the key target of a large number of drugs, scientists have now been able to show more precisely how these receptors act in the cell interior...
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Promising therapeutic approach for improving mitochondrial function
Scientists have made progress in the development of products that improve mitochondrial function...
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New UK research centre for antimicrobial drug development
A state-of-the-art research centre to help accelerate the development of new antibiotics is set to be established by the University of Liverpool.
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New tool developed to help avoid adverse drug reactions
Medicines are an important part of treating and preventing disease in adults and children. The ideal medicine would have no side effects or adverse drug reactions (ADRs) as they are also called, but the reality is all medicines can cause unwanted effects, in some people.
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Orion research foundation grants €1 million for research
Orion and Finland are both celebrating their centenaries in 2017.
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Molecule activates pain relief and prevents high during medical marijuana use
Medicinal marijuana is used frequently as a painkiller for a variety of ailments and diseases yet its psycho active side effects are seen by many as a significant disadvantage.
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TSRI’s rat study shows how brain stores memories
A new study led by scientists at the Scripps Research Institute (TSRI) sheds light on how the brain stores memories.
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DiscoverX HitHunter® cAMP Assays
21 December 2016 | By DiscoverX Corporations
Optimized Assays for a Multitude of GPCR Applications...
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Versatile applications of next-generation sequencing in pharmaceutics
Next-generation sequencing (NGS) technologies hold great promise for unravelling the mysteries of biological systems, with the advent of DNA sequencing methods having greatly accelerated biomedical research, gaining broad applicability in disease diagnosis and therapeutics in recent years...
