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MedImmune and 3M partner to develop novel TLR agonist cancer therapies
25 September 2015 | By Victoria White
TLR agonists are promising agents that activate innate immune cells and enhance the visibility of cancer tumours...
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Oncology
Oncology is a branch of medicine that deals with the prevention, diagnosis and treatment of cancer.
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Study highlights the potential of FAK inhibition in fighting cancer
25 September 2015 | By Victoria White
Researchers discovered that FAK inhibition can modulate the balance of immune cells in a tumour enabling an immune response to destroy the cancer cells...
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Should LC-MS/MS proteomics guide targeted drug selection for cancer patients?
History has demonstrated that the use of companion in vitro diagnostic tests to select cancer patients positive for a drug target significantly improves response to targeted anti-cancer therapies...
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BerGenBio presents positive preclinical data on BGB324
21 September 2015 | By Victoria White
The data highlights that BGB324 used in combination with immune checkpoint inhibitors in mouse carcinoma models showed enhanced tumour clearance compared with checkpoint inhibition alone...
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Researchers identify possible ovarian cancer biomarkers
17 September 2015 | By Victoria White
The researchers also determined that the level of biomarkers associated with ovarian cancer does not simply increase or decrease over the course of the disease...
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Amgen and Xencor enter cancer immunotherapy and inflammation collaboration
17 September 2015 | By Victoria White
The research collaboration brings together Amgen's capabilities in target discovery and protein therapeutics with Xencor's XmAb bispecific technology platform...
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Transatlantic partnership to develop treatments for pancreatic cancer
14 September 2015 | By Victoria White
The five-year programme will focus on the development of ‘nanomedicine’ in the treatment of pancreatic cancer, for which current treatment options are limited...
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SAS1B discovery could fundamentally alter cancer treatment
10 September 2015 | By Victoria White
The SAS1B protein appears only on egg cells and cancer cells, and could serve as a target for tiny tracking probes created using monoclonal antibodies...
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Wasp venom toxin MP1 blasts holes in cancer cells
4 September 2015 | By Victoria White
Research reveals exactly how the Polybia paulista wasp's venom toxin - called MP1 - selectively kills cancer cells without harming normal cells...
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Aspirin could boost cancer immunotherapy
4 September 2015 | By Victoria White
Researchers have shown that combining immunotherapy with aspirin or other COX inhibitors substantially slowed bowel and melanoma skin cancer growth in mice...
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Researchers use KG5 to sensitise tumours to radiation and chemotherapy
4 September 2015 | By Victoria White
Researchers have identified a pathway that causes resistance to chemotherapy and radiation treatments and a new drug, KG5, that targets this pathway...
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Genetic testing reveals new drug targets in oesophageal cancer
2 September 2015 | By Victoria White
Nearly all advanced oesophageal cancers harbour genetic mutations that can be targeted with emerging drug therapies, according to a new study...
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Oncodrone to progress prostate cancer drug with €2.5m grant
25 August 2015 | By Victoria White
Oncodrone, the anti-cancer company based in Nijmegen, has been granted a € 2,5 million Eurostars grant for the development of its lead drug OCD155...
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Oncology treatment pipeline offers significant opportunities
4 August 2015 | By Victoria White
The oncology drug pipeline is far larger than any other therapy area with 6,484 products in active development across all indications...
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St Jude scientists identify new mechanism of p53-induced cell death
31 July 2015 | By Victoria White
Researchers have identified a new mechanism that the tumour suppressor protein p53 uses to trigger cell death via apoptosis...
