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Immunotherapy

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DNA mutations shed in blood predicts response to immunotherapy

2 December 2017 | By Dr Zara Kassam (Drug Target Review)

Blood sample, or liquid biopsy, can reveal which patients will respond to checkpoint inhibitor-based immunotherapies...

webinar

Advancing the discovery of immunotherapeutics with large scale multiplexed experiments

27 September 2017 | By IntelliCyt Corporation

In this webinar, Belen Ybarrondo, Ph.D and Thomas Duensing, Ph.D discuss the challenges faced with antibody screening and how the iQue Screener can give an evaluation of cell killing mechanism, screening for immune checkpoint inhibitors and more...

whitepaper

Application note: A high-throughput, radioactivity-free assay for cell-mediated cytotoxicity

25 September 2017 | By IntelliCyt Corporation

In this application note, IntelliCyt Corporation demonstrate a fast, efficient, radioactivity-free CMC assay with low sample input requirements, enabling miniaturisation to 384-well plates, using the iQue® Screener...

Evaluating immunotherapeutic approaches with large scale functional assays for immuno-oncology

webinar

Evaluating immunotherapeutic approaches with large scale functional assays for immuno-oncology

22 September 2017 | By IntelliCyt Corporation

In this webinar, Belen Ybarrondo, Ph.D and Thomas Duensing, Ph.D discuss the need for robust high content tools for current immunotherapeutic approaches, and how IntelliCyt's iQue Screener PLUS can give functional efficacy of immuno-oncology therapies...

news

Cell surface protein may offer target in treating childhood cancers

12 September 2017 | By Dr Zara Kassam (Drug Target Review)

Immunotherapy drug candidate could be potent weapon against neuroblastoma and other paediatric malignancies...

news

New metabolic target in quest to control immune response

6 September 2017 | By Dr Zara Kassam (Drug Target Review)

Immune cells could help to increase immune activity in vaccines or suppress immune reactions in autoimmune diseases...

news

Immune system can be modulated by targeted manipulation

21 August 2017 | By Dr Zara Kassam (Drug Target Review)

Manipulation of the sugar metabolism and associated modulation of the immune system could open up new options for treating specific infectious and also autoimmune diseases...

news

Novel immunotherapy technology for prostate cancer

18 August 2017 | By Dr Zara Kassam (Drug Target Review)

Scientists have described a novel immunotherapeutic strategy for the treatment of cancer based on the use of synthetic DNA...

news

Researchers find switch that turns on immune cells tumour-killing ability

17 August 2017 | By Dr Zara Kassam (Drug Target Review)

Researcher have shown how a mRNA molecule known as Lethal-7 serves as a molecular control hub to direct the function of cytotoxic T lymphocytes...

news

Prospects identified for immunotherapy treatments

9 August 2017 | By Dr Zara Kassam (Drug Target Review)

A report published has identified the prospects of immunotherapy treatments...

news

CNIC scientists find the key to improved cancer immunotherapy

18 July 2017 | By Dr Zara Kassam (Drug Target Review)

The study demonstrates that tissue-resident and circulating memory T cells cooperate in anti-tumour immunity...

news

Extra funding for nanomaterials for cancer immunotherapy research

5 July 2017 | By Niamh Marriott (Drug Target Review)

The DFG has agreed to fund the Mainz-based Collaborative Research Center involved in the development of nanomaterials for cancer immunotherapy...

news

Arming T-cells to channel aggression against cancer

9 June 2017 | By Drug Target Review

Scientists have armed immune cells with a new surface molecule that causes them to respond aggressively when they encounter a protein that tumours actually use to camouflage themselves from the immune system. Researchers from the Helmholtz Zentrum München and various partners introduced the method in ‘Cancer Research’.

‘Immunoswitch’ particles may be key to more effective cancer immunotherapy

news

‘Immunoswitch’ particles may be key to more effective cancer immunotherapy

8 June 2017 | By Sarah Wills (Drug Target Review)

Scientists have created a nanoparticle that carries two different antibodies capable of simultaneously switching off cancer cells’ defensive properties while switching on a robust anti-cancer immune response in mice.

news

Scientists give tumour-fighting cells a boost in battling bone marrow cancer

2 June 2017 | By Niamh Marriott (Drug Target Review)

Researchers uncovered a new way to enhance the function of a specific type of immune cell that destroys tumours in multiple myeloma...

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Immunotherapy