news Gene therapy shows promise for Angelman syndrome treatment 26 October 2021 | By Anna Begley (Drug Target Review) A new gene therapy restored motor skill-learning and usual behaviours in Angelman syndrome mouse models, suggesting a novel therapy for the condition.
news Algorithm identifies cancer drugs to treat pulmonary hypertension 21 October 2021 | By Anna Begley (Drug Target Review) Scientists have identified potential cancer drugs to treat pulmonary hypertension using experimental and computational approaches.
news New single-cell and metagenomic technique can characterise microbes 14 October 2021 | By Anna Begley (Drug Target Review) The metagenomic method, termed SMAGLinker, could improve the accuracy and resolution of microbial characterisation to improve medicine design.
news Measuring microRNAs in blood may indicate dementia risk 14 October 2021 | By Anna Begley (Drug Target Review) Researchers identified three microRNAs whose levels were associated with mental performance in cells, mice and humans.
news Wyss Centre initiates collaboration to improve brain tumour treatment 13 October 2021 | By Anna Begley (Drug Target Review) The Wyss Centre has announced a collaborative project to improve understanding of the brain cancer glioblastoma and develop new personalised therapies.
news New vaccination approach could target “core” of all coronaviruses 12 October 2021 | By Anna Begley (Drug Target Review) Researchers have used genetically engineered SARS-CoV-2 Spike proteins to boost antibodies against a range of coronaviruses in mice.
news Discovery unveils genetic risk factor shared by Alzheimer’s and COVID-19 12 October 2021 | By Anna Begley (Drug Target Review) Scientists have identified the OAS1 gene as a risk factor for both Alzheimer's disease and COVID-19, suggesting potential drug targets.
news New drug target identified for myelodysplastic syndrome 8 October 2021 | By Anna Begley (Drug Target Review) Researchers have uncovered how mutations affecting RNA splicing alter cells to develop myelodysplastic syndrome (MDS).
news Scientists establish genetic link between HLA and genital warts 7 October 2021 | By Anna Begley (Drug Target Review) The discovery of a link between the human leukocyte antigen (HLA) and genital warts may lead to mRNA-based vaccines against HPV and other diseases.
news Two-week-old human embryos reveal origin of Huntington’s disease 6 October 2021 | By Anna Begley (Drug Target Review) Scientists have discovered a signalling pathway alteration in embryos with Huntington’s disease, paving the way for ground-breaking treatments.
news Nobel Prize for medicine awarded to temperature and touch discoveries 4 October 2021 | By Anna Begley (Drug Target Review) David Julius and Ardem Patapoutian have won the 2021 Nobel Prize for Physiology or Medicine, with their work being used to develop treatments for conditions such as chronic pain.
news Gene therapy method could restore visual function after stroke 4 October 2021 | By Anna Begley (Drug Target Review) Scientists have revealed a way to use gene therapy to turn glial brain cells into neurons, restoring vision and potentially restoring motor function.
news Zaki syndrome: the newly uncovered condition and its potential cure 1 October 2021 | By Anna Begley (Drug Target Review) Dubbed 'Zaki syndrome', the condition affects prenatal development of several organs and was identified using whole genome sequencing.
news CRISPR screening tool exposes new leukaemia drug target 29 September 2021 | By Anna Begley (Drug Target Review) A CRISPR screening tool identified a new target for acute myeloid leukaemia with fewer side effects than current approaches.
news CRISPR-based droplet method speeds up gene therapy research 28 September 2021 | By Anna Begley (Drug Target Review) The new CRISPR-based technology called MIC-Drop rapidly identified several genes for heart development and function in zebrafish.
