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Nanoparticle flu vaccine shows promise at protecting mice

25 May 2021 | By Victoria Rees (Drug Target Review)

Using nanoparticle liposomes, researchers have developed an experimental flu vaccine that has shown success in pre-clinical studies.

article

Protecting liposomes in COVID-19 mRNA vaccines could increase their stability

27 April 2021 | By Victoria Rees (Drug Target Review)

A team from the University of Texas at Dallas has shown that a novel buffer solution is effective at stabilising the liposomes and lipid nanoparticles in certain COVID-19 vaccines.

news

Gramicidin A antibiotic analogues safe for human cells developed

6 October 2020 | By Victoria Rees (Drug Target Review)

A team has developed 10 new versions of the antibiotic gramicidin A, which they say should be safe for use in pills or injections.

cancer cell in red being attacked by a white T cell

article

Developing IL-15 superagonists for cancer therapy

23 September 2020 | By Hannah Balfour (Drug Target Review)

Richard Sachse discusses how immunotherapies targeting interleukin 15 (IL-15) signalling can be optimised to enhance their efficacy and limit off-target effects.

news

Experimental formulation could be future for fast-acting insulin

2 July 2020 | By Hannah Balfour (Drug Target Review)

The novel formulation hit peak activity at nine minutes, less than half the time taken for a commercially available formulation.

bags of yellow-coloured blood plasma labelled for use as therapeutics

news

FDA and BARDA to collaborate with Grifols on COVID-19 therapeutics

30 March 2020 | By Hannah Balfour (Drug Target Review)

Grifols will leverage their resources to develop and test convalescent plasma-derived COVID-19 therapeutics in partnership with the FDA and BARDA.

Close up of IV drip, possibly delivering chemotherapy drugs to a patient

news

Ru-Pt conjugate drug could be the future for cancer therapies

16 March 2020 | By Hannah Balfour (Drug Target Review)

Researchers combined cisplatin, an enhancer and a photodynamic therapy (PDT) drug into a single conjugate that had 10 times the efficacy in treating treatment resistant cancer cells.

news

Alzheimer’s vaccine shows promising results in bigenic mice

3 January 2020 | By Hannah Balfour (Drug Target Review)

Researchers have created a new combination vaccine therapy that can induce strong immune responses against tau and Aβ pathologies seen in Alzheimer’s in bigenic mice.

news

Treatment for polycystic kidney disease shows promising results

13 September 2019 | By Rachael Harper (Drug Target Review)

A potential treatment for polycystic kidney disease has shown positive results in animal testing.

news

Potential sepsis prevention in burn patients found with novel approach

4 September 2019 | By Rachael Harper (Drug Target Review)

A new study has demonstrated the possibility of treating antibiotic-resistant Pseudomonas aeruginosa which causes sepsis in burn patients.

news

An interview with Bjorg K. Hunter, Device Engineering Manager from GSK ahead of Pre-Filled Syringes Europe 2018

20 November 2017 | By SMi Group

A debate on the impact of PFS regulation at Pre-Filled Syringes 2018...

news

Nemus Bioscience’s cannabis drug treats glaucoma in animal models

6 July 2017 | By Niamh Marriott (Drug Target Review)

Nemus Bioscience announced that THC derived from NB1111 achieved significant tissue concentrations in multiple compartments of the eye...

news

Study discovers proteins which suppress growth of breast cancer tumours

14 June 2017 | By Niamh Marriott (Drug Target Review)

Researchers have found that a type of protein could hold the secret to suppressing the growth of breast cancer tumours.

news

Dartmouth tuberculosis vaccine passes important milestone

12 May 2017 | By Niamh Marriott (Drug Target Review)

Investigators at Dartmouth's Geisel School of Medicine announced that two new studies of DAR-901, their investigational vaccine against tuberculosis (TB), have moved it to the forefront of new vaccines in development for global control of this deadly infectious disease.

news

BioPharmaSpec to expand in-house analytical capabilities

11 May 2017 | By Niamh Marriott (Drug Target Review)

For characterising higher order protein structure and accurately defining CQAs of biopharmaceuticals...

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