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Epigenetic compound inhibits the growth of melanoma cells
Researchers have developed a compound that successfully inhibits the growth of melanoma cells by targeting specific epigenetic modifying proteins...
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Epigenetics
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Alpha technology
3 January 2018 | By PerkinElmer
Alpha (Amplified Luminescence Proximity Homogeneous Assay) bead-based technology for no-wash assays.
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CRISPR-dCas9 reveals surprising insight into breast cancer development
Changing the epigenetic code of a single gene is enough to cause a healthy breast cell to become abnormal...
article
Expert view: Overcoming NGS obstacles
Using next-generation sequencing techniques enables pharmaceutical companies to explore the molecular landscape of disease initiation and progression with unprecedented clarity. Dr Sam Rulli, Product Manager at QIAGEN, provides his insight into the major challenges researchers face...
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Expert view: The future of single-cell sequencing
The power of single-cell sequencing and its application in the field of oncology remains a top opportunity for discoveries that could have a huge impact on improving human health worldwide. However, barriers remain before those studies can be furthered...
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Breakthrough method yields trove of neuronal subtypes and gene regulators
Researchers have discovered a trove of neuronal subtypes and gene regulators, using a new method they developed called snmC-seq...
article
CRISPR-Cas9 repairs genetic mutation in human embryos
"Well thought through and brilliantly executed" study shows different DNA-repair mechanism in embryos compared to iPSCs
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DNA: discovering a new mechanism of epigenetic inheritance
Scientists have demonstrated the existence of transgenerational epigenetic inheritance (TEI) among Drosophila fruit flies...
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Link discovered between immune system, brain structure and memory
The body's immune system performs essential functions, such as defending against bacteria and cancer cells. However, the human brain is separated from immune cells in the bloodstream by the so-called blood-brain barrier. This barrier protects the brain from pathogens and toxins circulating in the blood, while also dividing the immune…
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Changes in RNA splicing: a new mechanism for genetic risk in schizophrenia
New research has identified sections of DNA associated with altered regulation of gene expression underlying schizophrenia.
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Obesity can reprogram muscle stem cells
Obesity is associated with reduced muscle mass and impaired metabolism. Epigenetic changes that affect the formation of new muscle cells may be a contributing factor, according to new research from Lund University, Sweden.
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How to stop pain from serious burns using epigenetics
The unpleasant sensation sparked by the nervous system when confronted with a harmful stimulus can be alleviated by blocking a genetic marker that switches off the activity of the neurons involved.
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Oncology collaboration: Proteros & MSD to find epigenetic target
22 November 2016 | By Niamh Louise Marriott, Digital Content Producer
Proteros has entered into a second research agreement with Merck aimed at developing small molecule compounds against an additional epigenetic target...
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Epigenetics provides new insights into the pathogenesis of lymphoma
5 October 2016 | By Niamh Louise Marriott, Digital Content Producer
Epigenetics looks at special regulation mechanisms, such as DNA methylation and histone modifications, which determine the gene expression pattern...
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Cisbio Bioassays EPIgeneous™ biochemical and cellular assays
4 October 2016 | By Cisbio
Rapid advancements have been made in understanding the key role epigenetic modifications play in regulating cell activity and their implications on cell health and disease progression...
