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Enzymes are macromolecular biological catalysts. Enzymes accelerate, or catalyse, chemical reactions.
14 December 2015 | By Victoria White
A new study outlines a way of using antibiotic resistance to find chemicals capable of stopping amyloid formation in amyloid diseases such as Parkinson’s, Alzheimer’s and type II diabetes...
1 December 2015 | By Victoria White
The team from the Broad Institute and the McGovern Institute for Brain Research found that mutations in three amino acids dramatically reduced “off-target” cuts...
10 November 2015 | By Victoria White
The collaborations aim to identify and validate potential new therapeutic targets as well as identify biomarkers...
15 October 2015 | By Victoria White
Researchers have determined that the protein GPR3 might play an important role in alleviating the cognitive deficits of 'amyloid plaques'...
13 October 2015 | By Victoria White
Researchers have found that tamoxifen gives white blood cells a boost, better enabling them to respond to and kill bacteria in laboratory experiments...
28 September 2015 | By Victoria White
The newly described Cpf1 system differs in several important ways from Cas9, with significant implications for research and therapeutics...
24 September 2015 | By Victoria White
Deubiquitylating enzymes (DUBs) are involved in multiple cellular processes, including DNA damage and cell proliferation, and the inhibition of these enzymes has considerable potential for the generation of novel drugs...
21 September 2015 | By Drug Target Review
Included in this issue: Drug Development, Microfluidics, Proteomics, Ion Channels, GPCR, Imaging, Flow Cytometry, Enzymes
In much the same way that kinases and phosphatases attach and remove phosphate groups from proteins to modulate their activity, there are a series of enzymes (E1, E2, E3) that add one or more ubiquitins onto a protein, as well as enzymes that remove them (deubiquitinases; DUBs), thereby regulating their…
2 September 2015 | By Victoria White
ESCMID advocates the need for greater education, guidance and research on the build-up, treatment and prevention of biofilms...
1 September 2015 | By Nick Jackson
Dr Koslowski brings over 15 years’ experience across biopharmaceutical research and development, specialising in drug target discovery and clinical validation...
19 August 2015 | By Victoria White
Roche has signed a definitive agreement to acquire Kapa Biosystems, strengthening Roche's next-generation sequencing product offerings...
6 August 2015 | By Victoria White
MedImmune has entered into an exclusive clinical trial collaboration with Mirati Therapeutics to evaluate durvalumab in combination with mocetinostat...
30 July 2015 | By Victoria White
Researchers have engineered a tethered ribosome that may enable the production of new drugs and next-generation biomaterials...
26 June 2015 | By Victoria White
UIC Researchers have identified a molecular mechanism that directs embryonic stem cells to mature into endothelial cells...
