What are the pros and cons of using organoids?
Dr Shona Lang investigates the advantages and disadvantages of using organoids within R&D, highlighting the most important questions to ask before using these models.
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Dr Shona Lang investigates the advantages and disadvantages of using organoids within R&D, highlighting the most important questions to ask before using these models.
A protein discovery could lead to a new and highly potent immune-therapeutic drug for the eradication of cancers using natural killer cells.
MSD and the Francis Crick Institute will work together on a project to identify disease targets for motor neuron disease.
New computer model that simulates the way red blood cells become misshapen by sickle cell disease could identity promising drug candidates.
Designing new drug molecules is crucial to R&D. Dr Sam Genway suggests that one way to improve and speed up this process is using AI inspired by language translation.
A research team has developed a method for regenerating old brain stem cells from rat models, which could be used to treat age-related brain diseases.
A new technique called ‘ubiquitin clipping’ has been created which could aid proteomics research and the development of new drugs for ubiquitination.
Imaging methods are used by scientists to identify therapeutic targets and improve drug efficacy. This article lists five of the latest developments for imaging techniques.
Using a compound called PTC596 in combination with other drugs, researchers effectively treated pancreatic cancer in mice.
Researchers hope the system can choose the right patients to enroll in clinical trials, to speed discovery of drug treatments.
Researchers have extended the life of heart segments from 24 hours to six days, enabling pre-clinical trials to experiment on these new models for longer periods of time.
A novel antibody-enzyme fusion therapeutic strategy for Lafora disease has shown effectiveness in pre-clinical study mice models.
A study has shown that mice and rats become stressed when housed alone, affecting results of pre-clinical trials.
Researchers have identified a protein that plays a role in promoting blood cancer and have successfully used a novel compound to inhibit it, reducing tumour growth.
A new study has shown that proteins derived from the oncogene, KRAS, can transfer between colon cancer cells.