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CRISPR technique identifies Alzheimer’s biomarker

10 October 2018 | By Drug Target Review

UEx researchers have identified a potential biomarker for Alzheimer's disease using the CRISPR gene editing technique to analyse brain samples...

news

Elrig 2018: Drug discovery using small and large molecules

9 October 2018 | By Iqra Farooq (Drug Target Review)

The Drug Target Review team are at Elrig Drug Discovery 2018 in the London ExCel...

news

Prenatal gene editing used in treating congenital disease before birth

9 October 2018 | By Drug Target Review

Researchers show the first example of a base-editing tool to treat a disease in utero in animal models...

news

Biodegradable devices speed up nerve regeneration

9 October 2018 | By Drug Target Review

Researchers have developed an implantable and biodegradable device to aid the regeneration of nerve after damage from accidents and sports injuries...

news

Scientists create map of brain region linked to Alzheimer’s disease

8 October 2018 | By Drug Target Review

Scientists have mapped areas of the brain that are linked to Alzheimer's disease to deliver genetically-targeted drugs to specific neurons...

news

Efficacy of PET imaging in managing chronic liver diseases

8 October 2018 | By Drug Target Review

PET imaging could be used as a non-invasive substitute to painful and complicated liver biopsies for chronic liver disease...

news

Researchers develop a potential tool for efficacious targeted cancer therapy

8 October 2018 | By Drug Target Review

Researchers have developed PeptiENV, a cancer vaccine platform, which can be used to improve the therapeutic efficacy of oncolytic enveloped viruses...

news

Prostate and lung cancers driven by common mechanisms

5 October 2018 | By Iqra Farooq (Drug Target Review)

Lung and prostate small cell carcinomas are driven by common mechanisms, which could lead to the development of one treatment for all small cell cancers...

news

Estradiol exerts anticancer effects in triple-negative breast cancer

5 October 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have identified the drug estradiol as a potential new treatment for a subset of women with triple-negative breast cancer...

news

Nonresponsive NK cells directly impact malaria severity

5 October 2018 | By Drug Target Review

The failure of natural killer cells (NK cells) to respond to infection explains why malaria causes a worse reaction in some patients than others.

news

RNA-seq of 20,000 cardiac cells reveals heart disease insights

5 October 2018 | By Iqra Farooq (Drug Target Review)

RNA analysis of 20,000 cardiac cells from heart tissue in both ordinary and deceased mice showed an insight to the development of heart disease...

article

Exploring quality of life for stoma patients

4 October 2018 | By Drug Target Review

There are many people with a stoma living in the community in the UK. A commonly reported problem with living with a stoma is a poor quality of life because of uncertainty and doubts in the mind of the person with a stoma. The focus of this article is reviewing…

news

Chemotherapy and APOE4 linked to cognitive issues

4 October 2018 | By Iqra Farooq (Drug Target Review)

Both human and mouse models show that chemotherapy and APOE4 are linked to cognitive issues faced by patients who overcome cancer...

news

Nuclear tracer helps to study the aging brain

4 October 2018 | By Drug Target Review

A PET nuclear tracer could help researchers to understand neurodegeneration in aging brains better, as it enters the brain and distributes quickly...

news

SERDs molecules could spur a new class of drugs for breast cancer

4 October 2018 | By Drug Target Review

Stevens researchers design and develop a new class of molecules for breast cancer therapy...

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