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Possible treatment discovered for severe dengue disease
New findings suggest a possible new treatment strategy for severe dengue disease using the tryptase inhibitor, nafamostat mesylate.
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Succinate in cystic fibrosis lungs feeds deadly bacteria
Targeting a deadly bacteria's use of succinate in the lungs could control infection and improve the health of people with cystic fibrosis.
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Gene linked to rare disorder also regulates key enzyme in Alzheimer’s
A gene associated with a rare balance disorder also regulates the behaviour of an enzyme that increases the risk for Alzheimer's disease.
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Osteoporosis in mice reversed with new drug target
A pharmaceutical target has been identified by Duke University that, when activated, can reverse bone degradation caused by osteoporosis.
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New drug target for glioblastoma identified by study
A new drug target for treating glioblastoma has been identified from a cellular pathway found to contribute to the spread of glioma stem cells.
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Electrical channels in retina could play role in degenerative diseases
Researchers have discovered electrical channels important in sensory cell renewal which could be studied further to develop therapies for retinal diseases.
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New CRISPR technique could alter the way we look at brain diseases
Researchers may have fundamentally altered the way scientists study brain diseases with new CRISPR technology.
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Genes linked to Alzheimer’s risk have been identified
Two genes that influence risk Alzheimer's disease could provide scientists with new targets for delaying the onset of the condition's symptoms.
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Blood-brain barrier role in Alzheimer’s patients revealed by tissue model
A new study has found that damage caused by Alzheimer's allows toxins to enter the brain, further harming neurons.
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Parkinson’s disease symptoms “improved” by oestrogen
New research into sex-based differences of Parkinson's disease could lead to new treatments.
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Direct toxic action of beta-amyloid in Alzheimer’s patients identified
The cause and trigger of the large clumps of protein beta-amyloid found in the brains of early-stage Alzheimer's patients have been discovered.
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Five newest developments for imaging in drug research
Imaging methods are used by scientists to identify therapeutic targets and improve drug efficacy. This article lists five of the latest developments for imaging techniques.
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Potential treatment target identified for Crohn’s disease
Researchers have identified a pathway in the immune system activated in Crohn's disease which could lead to investigating new treatments.
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CRISPR-Cas used to edit cystic fibrosis gene mutations
A research team have used genome editing to correct two of the mutations that cause cystic fibrosis.
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Experimental treatment slows prion disease
A new experiment has not only slowed the progression of the prion disease, scrapie, it also extended the lives of prion-infected mice
