news Study finds astrocytes critical in progression of Huntington’s disease 18 October 2019 | By Victoria Rees (Drug Target Review) The new research shows that astrocytes contribute to Huntington’s disease symptoms, but suppressing a mutation stops the disease from progressing.
news Full gene-replacement model developed for Alzheimer’s MAPT gene research 17 October 2019 | By Drug Target Review Researchers in the US have successfully produced a mouse model with a human MAPT gene to enable more accurate research into Alzheimer’s therapy.
news Selective inhibitor could reduce resistance to cancer therapies 16 October 2019 | By Victoria Rees (Drug Target Review) A study has found a selective inhibitor for an enzyme that allows cancer cells to mutate and become resistant to treatments.
news Dementia spreads via connected brain networks, finds study 15 October 2019 | By Victoria Rees (Drug Target Review) New findings on dementia reveal that brain atrophy spreads via connected brain networks, rather than simply adjacent areas of the brain.
news Researchers develop new immuno-oncology technique 15 October 2019 | By Victoria Rees (Drug Target Review) A team has used viral gene editing and CRISPR to form a system that marks tumours for destruction, potentially improving immunotherapies.
news Microglia critical for neurodegeneration in mice, study finds 14 October 2019 | By Victoria Rees (Drug Target Review) Microglia brain immune cells are vital in conjunction with the APOE4 gene during the development of Alzheimer’s in mouse models, researchers have found.
news Bacterial strain identified that determines fate for rotavirus sufferers 10 October 2019 | By Drug Target Review Scientists in the US have identified a particular bacterial strain, Segmented filamentous bacteria (SFB), that can prevent and cure rotavirus in mice.
news New therapeutic target identified for pulmonary fibrosis 10 October 2019 | By Rachael Harper (Drug Target Review) A genetic mutation that causes idiopathic pulmonary fibrosis has been identified and could lead to a new therapeutic approach to treating the disease.
news Study reveals potential of gamma delta T cells to combat breast cancer 9 October 2019 | By Victoria Rees (Drug Target Review) Researchers have discovered that a specific subset of gamma delta T cells can be found in higher numbers of breast cancer survivor tissue, indicating its role in fighting the condition.
news Research reveals calcium signalling pathway in T cells 9 October 2019 | By Victoria Rees (Drug Target Review) A study has uncovered the mechanism behind calcium entry and exit into T cells, which could be used in development of autoimmune disease treatments.
news Sir Peter Ratcliffe awarded joint Nobel Prize for Physiology or Medicine 8 October 2019 | By Victoria Rees (Drug Target Review) The researcher Sir Peter Ratcliffe and two others have been jointly awarded the Nobel Prize for Physiology or Medicine 2019.
news Potential treatment for heart attacks discovered by researchers 4 October 2019 | By Victoria Rees (Drug Target Review) Researchers have uncovered a treatment that may be used to treat heart attacks or to prevent heart failure, using the circadian clock.
news NKAP gene mutation linked to rare developmental disease 3 October 2019 | By Victoria Rees (Drug Target Review) A study has revealed that a mutation in the NKAP gene causes a rare syndrome, providing researchers with the potential to develop treatments for the condition.
news Nipah and Hendra virus attack neutralised by potent antibody 30 September 2019 | By Rachael Harper (Drug Target Review) Researchers have shown that a monoclonal antibody prevents viruses from fusing with cell membranes to gain entry.
news Neuronal link between chronic pain and depression discovered 27 September 2019 | By Victoria Rees (Drug Target Review) The mechanism in the brain connecting chronic pain and depression could lead to treatments for both, according to researchers.
