news Brain Atlas enables exploration of the brain proteome 6 March 2020 | By Hannah Balfour (Drug Target Review) International researchers have analysed nearly 1,900 brain samples to create the Brain Atlas, the latest database released by the Human Protein Atlas (HPA) project.
news Self-assembling biomaterial could be used to model vascular structures 5 March 2020 | By Hannah Balfour (Drug Target Review) Scientists have shown an innovative new biomaterial made of graphene oxide and proteins could be used to 3D print model vascular structures.
news Scientists demonstrate how COVID-19 infects human cells 5 March 2020 | By Hannah Balfour (Drug Target Review) Researchers have used cryogenic electron microscopy to show that coronaviruses enter human cells through an interaction with angiotensin-converting enzyme 2 (ACE2).
news Blocking bacterial competence could prevent antibiotic resistance 4 March 2020 | By Hannah Balfour (Drug Target Review) Scientists suggest competence-blocking, ‘anti-evolution’ drugs could be administered alongside antibiotics to prolong the period before bacterial resistance emerges.
news Mechanism of action revealed for remdesivir, potential coronavirus drug 3 March 2020 | By Victoria Rees (Drug Target Review) Researchers have demonstrated how the drug known as remdesivir works, presenting the viral RNA polymerase of coronaviruses as a target for these conditions.
news ZT-1a compound could be an alternative to surgery for brain swelling 3 March 2020 | By Hannah Balfour (Drug Target Review) Rodent models of stroke and hydrocephalus treated with ZT-1a had reduced brain swelling, according to scientists.
article Rebalancing the immune system to treat autoimmune disease 2 March 2020 | By Hannah Balfour (Drug Target Review) Dr Nicolas Poirier reveals how immunotherapies can be designed to recalibrate the immune system for long-term maintenance of autoimmune remission.
news Stainless imaging developed by adding infrared to standard microscopes 2 March 2020 | By Victoria Rees (Drug Target Review) A new method to image cancerous tissues has been created by researchers who have paired infrared measurements with high-resolution optical images.
news Inhaling stem cell secretome could be a more effective pulmonary fibrosis treatment 2 March 2020 | By Hannah Balfour (Drug Target Review) Rodent models of pulmonary fibrosis have been used to show that lung spheroid cell secretome therapy is as effective as stem cell secretome treatment.
news Metal-containing compounds could lead to new antibacterials 2 March 2020 | By Hannah Balfour (Drug Target Review) International collaboration has shown that compounds with metals in them show antibacterial activity against MRSA, E. coli and A. baumannii.
news Study reveals how immune system handles fungal and viral infections 28 February 2020 | By Victoria Rees (Drug Target Review) Researchers have studied how the human body responds to viral infection when already infected by fungi, offering insights into the immune system.
news Naphthyridine-Azaquinolone reverses Huntington’s DNA repeats in mouse model 28 February 2020 | By Hannah Balfour (Drug Target Review) Researchers show Naphthyridine-Azaquinolone (NA) could be a possible future therapy able to slow the progression and improve the symptoms of Huntington’s disease.
news New T-cell discovery could lead to treatments for both bacterial infections and autoimmune conditions 28 February 2020 | By Hannah Balfour (Drug Target Review) A novel highly activated form of T cells could be suppressed to treat autoimmune conditions and activated in treating bacterial infections.
news Boosting natural killer cells in mice with eczema relieves condition 28 February 2020 | By Victoria Rees (Drug Target Review) Researchers have found that using IL-15 to boost natural killer cell numbers in mice helps to combat eczema and could be a therapeutic strategy for patients.
news Possible novel cognitive anti-ageing targets identified 27 February 2020 | By Hannah Balfour (Drug Target Review) Researchers have shown that two epigenetic regulators could be targeted to improve cognitive and behavioural decline in age-related diseases like Alzheimer’s.
