news Targeting innate immunity with Transcreener® Assays 25 June 2020 | By BellBrook Labs Over the past year, BellBrook Labs has leveraged its Transcreener HTS Assay technology to build enabling products and services focusing on innate immunity targets.
news Over 718 drugs in pipeline as potential COVID-19 treatments, says report 25 June 2020 | By Victoria Rees (Drug Target Review) New research has found that of the 718 pipeline drugs associated with COVID-19, 70 percent are currently in the discovery or pre-clinical stages.
news CD47 blockade could work as immunotherapy across multiple diseases 24 June 2020 | By Victoria Rees (Drug Target Review) Researchers have demonstrated that blocking CD47-mediated signalling in mice can enhance the speed of pathogen clearance, presenting a new potential form of immunotherapy.
news Open source all-atom model of entire COVID-19 S protein released 23 June 2020 | By Victoria Rees (Drug Target Review) Researchers have developed a video and model-building programme for other scientists to build full-length COVID-19 S protein models.
news N terminal domain of S protein revealed as antibody target for COVID-19 23 June 2020 | By Victoria Rees (Drug Target Review) An antibody with high neutralising potency against SARS-CoV-2 that binds to the N terminal domain of the Spike protein has been identified by a team researching COVID-19 therapeutics.
news Method to convert any mouse into COVID-19 model made available to researchers 22 June 2020 | By Victoria Rees (Drug Target Review) Researchers who reported that delivering the human ACE2 protein into mouse airway cells creates COVID-19 models have released their findings to allow other scientists to make their own models.
news MMR vaccine could protect against COVID-19 sepsis, paper says 22 June 2020 | By Victoria Rees (Drug Target Review) Researchers have suggested that the MMR live attenuated vaccine could be used to provide non-specific protection to patients against sepsis associated with COVID-19.
article 3D bioprinting COVID-19 lung models for drug development 19 June 2020 | By Hannah Balfour (Drug Target Review) Keith Murphy, CEO of Viscient Biosciences, discusses the process of developing a 3D bioprinted tissue model and their potential in developing therapeutics for COVID-19 and other diseases.
news Biomarker suggests COVID-19 could cause brain injury in patients 19 June 2020 | By Victoria Rees (Drug Target Review) Researchers have found that a neurofilament named NfL is heightened in COVID-19 patients who require ventilator treatment, so could serve as a biomarker for the disease.
news Researchers identify link between pancreatic cancer-driving mutations 19 June 2020 | By Victoria Rees (Drug Target Review) A study has shown that p53 rewires RNA splicing which leads to further activation of the KRAS oncogene, presenting a target for the progression of pancreatic cancer.
article Why are women underrepresented in COVID-19 research authorship? 17 June 2020 | By Victoria Rees (Drug Target Review) An analysis of papers relating to COVID-19 has found that female researchers make up a third of authors. Here, the potential reasons behind this figure are explored and a possible solution to encourage equality.
news COVID-19 poses threat to entire nervous system, says study 15 June 2020 | By Victoria Rees (Drug Target Review) Following an analysis of scientific literature, researchers say that COVID-19 may affect the entire nervous system, including the brain, spinal cord, nerves and muscles.
webinar Improving cell-based assays and their future in drug discovery 15 June 2020 | By Horizon Discovery Watch our on-demand webinar with Horizon Discovery which summarises the challenges in translating promising pre-clinical therapeutic candidates into clinical success.
news Link identified between COVID-19 and onset of diabetes 15 June 2020 | By Victoria Rees (Drug Target Review) New research indicates COVID-19 could trigger the development of diabetes in healthy people, prompting experts to establish a registry for COVID-19 and diabetes data.
whitepaper Whitepaper: Virus-laden particle detection in the air 12 June 2020 | By Bertin Instruments Read application notes and best practices for optimised environmental detection and monitoring of airborne viruses with Coriolis® Air Samplers.
