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Researchers discover mechanism behind severe cases of G6PD deficiency
Researchers have revealed how the most severe cases of G6PD deficiency occur, which could help scientists design new drugs for the disease.
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Disease research
webinar
CRISPR screening to identify new drug targets in regulatory B cells and other immune cells
15 January 2021 | By Horizon Discovery
Watch our on-demand webinar where we discuss how CRISPR screening is proving to be a robust platform for the identification and validation of new biological targets for disease treatment. It is hoped that CRISPR screens will accelerate drug development by providing more robust targets for validation than siRNA screens, for…
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Recovered COVID-19 patients may be protected, but they could still transmit the virus
According to a Public Health England study, prior SARS-CoV-2 infection provides 83 percent protection against reinfection but may not stop individuals spreading COVID-19.
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Artificial intelligence analyses how viruses evade the immune system
The natural language processing model trained using viral protein sequence data was able to predict promising targets for vaccines against HIV, influenza and coronaviruses.
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New probes shine a light on the role of four-stranded DNA in human cells
A better understanding of the role of four-stranded DNA (G-quadruplex) could enhance cancer therapeutics, said the developers of the probes.
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SARS-CoV-2 infects CNS and damages brain tissue, study shows
Researchers have shown in cells and models that the central nervous system and neurons can become a target of SARS-CoV-2 infection.
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Study reveals novel targets for treating atopic dermatitis
Understanding how Staphylococcus aureus bacteria colonises skin affected by atopic dermatitis could lead to new treatments that help prevent the spread of antibiotic resistance, say scientists.
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Microbiome may influence severity of COVID-19, researchers say
A study has revealed that the microbiome could impact COVID-19 severity and may be implicated in persisting inflammatory symptoms.
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Novel human alveolar tissue model could help COVID-19 drug development
Researchers will use the in vitro model to study how respiratory viruses, like SARS-CoV-2, cause Acute Respiratory Distress Syndrome (ARDS) and develop potential interventions.
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Immune cells discovered in lungs improve flu defence, study shows
A team has found immune cells in the lungs after infection from the flu, which protected mice against reinfection from a different strain.
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SARS-CoV-2 introduced to UK more than 1,000 times before March, says genomic analysis
Researchers show that genomic tracking can be used to trace individual virus transmission lineages and could therefore be adopted for future pandemics.
whitepaper
Whitepaper: Remdesivir: The technologies behind the discovery
Remdesivir is being prescribed under FDA emergency use authorisation as a treatment for patients with COVID-19.
video
Webinar: Targeting oxygen sensing in cancer
This webinar from Bio-Techne discusses canonical and alternative oxygen sensing mechanisms implicated in cancer therapy resistance and recurrence.
news
Novel intestine model could accelerate the development of treatments
The transparent millifluidic perfusion cassettes (mPCs) developed by researchers should allow for better evaluations of the interactions between the cells and invading pathogens.
news
Researchers develop comprehensive database of head and neck cancer
A new study has revealed a range of genomic, proteomic and transcriptomic data about head and neck cancers, presenting possible treatment strategies.
