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New way to target treatment-resistant cancers identified
A new mechanism by which cancer cells become resistant to chemotherapy has been found which could lead to a new target for drugs.
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chemotherapy
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Chemotherapy resistance pathway identified for NSCLC
A study has discovered the mechanism behind NSCLC resistance to chemotherapy, which could improve treatment strategies for the condition.
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Study reveals how to make pancreatic cancer chemotherapy more effective
Researchers have shown that blocking a particular enzyme causes chemotherapy to become more effective against pancreatic cancers in pre-clinical studies.
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Study identifies protein key to successful chemotherapy
A protein has been discovered as key for effective chemotherapy, meaning improved treatments for chemotherapy resistance can be developed.
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Researchers identify chemotherapy-enhancing molecule
A new study has found a small molecule which prevents cancer cells from mutating and becoming resistant to chemotherapy.
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New drug Metavert blocks growth of pancreatic cancer in mice
Scientists in California have discovered that a newly developed drug prevents pancreatic cancer in lab mice.
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Researchers successfully use AI to facilitate dynamic dosing for metastatic cancer
Scientists have harnessed a powerful artificial intelligence (AI) platform, CURATE.AI, to successfully treat a patient with advanced cancer by completely halting disease progression, representing a big step forward in personalised medicine.
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GC4419 could prevent debilitating side effect of cancer treatment
Researchers are reporting on a new drug that can treat the painful and debilitating side effect of severe oral mucositis (SOM)...
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CBD improves survival rates of mice with pancreatic cancer
Mice with pancreatic cancer that were treated with CBD alongside chemotherapy, survived almost three times longer than those treated with chemotherapy alone...
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Cancer drug screening: the historical perspective
Chemotherapy with cytotoxic and growth inhibitory drugs have played an important role in cancer therapy, used either alone or in combination with other treatment modalities such as surgery, radiation or biological therapy. Chemotherapy, in most instances, was the only alternative treatment for metastatic cancer – mainly given as drug combinations...
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Screening In-Depth Focus 2018
This In-Depth Focus reviews the history of cancer treatments, looks at improving the translation of disease biology though phenomics, and considers how to enhance cell bioprocessing through cell-based combinatorial culture.
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Scientists mine gene responses to existing chemotherapies to facilitate precision cancer treatment
Scientists utilise computational biology techniques in a bid to enable doctors to use targeted therapies for cancer patients.
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Man-made antibodies show promise in attacking cancer cells in animal models
Molecules called aptamers could form new, safer chemotherapy delivery systems...
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SLU scientist turns off chemo pain in the laboratory
Saint Louis University researchers have had success in an animal model in turning off the excruciating pain that often accompanies a colorectal cancer drug.
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Turning off autophagy helps chemotherapy stress cancer cells to death
A study has pinpointed a molecule that links autophagy and apoptosis, namely a transcription factor called FOXO3a.