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Biomarkers are a naturally occurring molecule, gene, or characteristic by which a particular disease can be identified.
Next-generation sequencing (NGS) technologies hold great promise for unravelling the mysteries of biological systems, with the advent of DNA sequencing methods having greatly accelerated biomedical research, gaining broad applicability in disease diagnosis and therapeutics in recent years...
15 November 2016 | By Niamh Louise Marriott, Digital Content Producer
B is for Biomarkers - the next instalment of our daily pharmaceutical alphabet bringing you up to date with all the latest news and research on the subject of biomarkers.
5 October 2016 | By Niamh Louise Marriott, Digital Content Producer
Epigenetics looks at special regulation mechanisms, such as DNA methylation and histone modifications, which determine the gene expression pattern...
Researchers at Rush Medical Center are developing novel diagnostic tests to help guide treatment decisions for patients with non-small cell lung cancer...
5 September 2016 | By Niamh Louise Marriott, Digital Content Producer
The loss of CHD1, one of the most mutated genes in prostate tumours, sensitises human prostate cancer cells to different drugs, a biomarker for...
Starting in the 1970s, the drug discovery research process changed dramatically. Our understanding of biological targets and pathways grew and the largely empirical and target agnostic in vivo pharmacology approach was replaced with target-centric methods...
28 July 2016 | By DiscoverX Corporation
In vitro detection of potential in vivo toxicity and adverse events...
30 June 2016 | By Victoria White, Digital Content Producer
The partnership will allow Probiodrug to utilise Crossbeta’s proprietary technology in support of Probiodrug’s biomarker development activities...
9 June 2016 | By Victoria White, Digital Content Producer
A new method, developed by UCLA scientists, could eventually lead to a way to improve accuracy of how well a patient will respond to treatment...
Volume 1 2016 of EMD Millipore's "Analyte Quarterly" provides details of all their Immunoassays & MILLIPLEX® map Kits...
12 April 2016 | By Victoria White, Digital Content Producer
A team of scientists have identified new biomarkers for TB which have shown for the first time why immunity from the widely used BCG vaccine is so variable...
12 April 2016 | By Victoria White, Digital Content Producer
The discovery means that a family history of DCIS could be as important to assessing a woman’s risk as a history of invasive breast cancer...
8 April 2016 | By Victoria White, Digital Content Producer
A study found that in addition to decreased overall tumour burden, mice lacking epiregulin also showed reduced inflammation...
Non-alcoholic fatty liver disease (NAFLD), a consequence of sedentary life styles and high fat diets, has an estimated prevalence of about 30% in western countries. It is associated with insulin resistance, obesity, glucose intolerance and drug toxicity. Additionally, polymorphisms within genes such as PNPLA3, TM6SF2, APOC3, NCAN and PPP1R3B correlate…
15 March 2016 | By Victoria White
A division of SRI International will conduct preclinical studies to assess the efficacy of compounds or vaccines for preventing invasive-cancer development...
