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Therapeutics

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FDA and BARDA to collaborate with Grifols on COVID-19 therapeutics

30 March 2020 | By Hannah Balfour (Drug Target Review)

Grifols will leverage their resources to develop and test convalescent plasma-derived COVID-19 therapeutics in partnership with the FDA and BARDA.

outlines of coronavirus particles in white on a red background

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Remdesivir most promising COVID-19 drug, say researchers

27 March 2020 | By Hannah Balfour (Drug Target Review)

A review of potential COVID-19 therapeutics revealed that the most effective are likely to be those directly targeting SARS-CoV-2, such as remdesivir and tilarone.

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Collaboration initiated to develop COVID-19 immunotherapy

26 March 2020 | By Victoria Rees (Drug Target Review)

The University of Georgia and CEL-SCI Corporation have partnered to develop an immunotherapy to combat the COVID-19 coronavirus using the Ligand Antigen Epitope Presentation System (LEAPS) technology.

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Map of COVID-19 and human protein interactions reveals drug targets

24 March 2020 | By Victoria Rees (Drug Target Review)

Researchers have identified which SARS-CoV-2 proteins physically associate with proteins in human cells, revealing potential drug targets to treat the COVID-19 coronavirus.

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Researchers to screen compound library for antiviral drugs to combat COVID-19

23 March 2020 | By Victoria Rees (Drug Target Review)

Scripps Research has announced it will screen over 14,000 compounds to see if any present significant activity against COVID-19, for use in a therapeutic.

Coronavirus particles in green with purple extracellular proteins

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Preliminary SARS-CoV-2 protease inhibitor shows efficacy in mice

20 March 2020 | By Victoria Rees (Drug Target Review)

Using X-ray crystallography, researchers have revealed the structure of the SARS-CoV-2 main protease, designing an inhibitor to bind to this target and prevent viral replication.

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Understanding of COVID-19 infections in children will aid treatment development, say researchers

20 March 2020 | By Victoria Rees (Drug Target Review)

A statement from scientists has highlighted that improving the understanding of COVID-19 infections in children will help researchers to develop better treatments.

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Collaboration to co-develop antibody products for treating COVID-19

17 March 2020 | By Victoria Rees (Drug Target Review)

AbCellera and Eli Lilly have announced their partnership to develop, manufacture and distribute antibody treatments for the COVID-19 coronavirus.

news

Mechanism of action revealed for remdesivir, potential coronavirus drug

3 March 2020 | By Victoria Rees (Drug Target Review)

Researchers have demonstrated how the drug known as remdesivir works, presenting the viral RNA polymerase of coronaviruses as a target for these conditions.

news

Coronavirus update: recent developments in vaccine research

27 February 2020 | By Hannah Balfour (Drug Target Review)

Drug Target Review’s round-up of the latest developments in 2019 novel coronavirus (COVID-19 or SARS-CoV-2) therapeutics and vaccines.

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Therapeutics