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SARS-CoV-2 and immunology: antibody developments

15 February 2021 | By Victoria Rees (Drug Target Review)

Discover the latest in SARS-CoV-2 antibody research as we cover three of the most recent developments in this article.

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Majority retain COVID-19 antibodies for six months after infection

3 February 2021 | By Victoria Rees (Drug Target Review)

A study has shown that 88 percent of people infected by COVID-19 were able to produce SARS-CoV-2 antibodies after six months.

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Thapsigargin could be used as antiviral to treat COVID-19, study shows

3 February 2021 | By Victoria Rees (Drug Target Review)

Researchers have discovered that thapsigargin has novel antiviral properties and is effective against COVID-19 in pre-clinical studies.

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Novel protein could neutralise SARS-CoV-2 infection in kidneys

2 February 2021 | By Victoria Rees (Drug Target Review)

A new protein can trick SARS-CoV-2 and bind to the Spike protein rather than cell membranes in a kidney organoid.

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T cells target broad range of SARS-CoV-2 epitopes, study shows

29 January 2021 | By Victoria Rees (Drug Target Review)

A study has found that T cells combat SARS-CoV-2 by targeting many sites on the coronavirus, not just the Spike protein.

Graphic of a person breathing in a stream of SARS-CoV-2 viral particles, some going down the throat to the lungs, others going up to the brain - idea of neurological symptoms of COVID-19

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New database to track neurological symptoms of COVID-19

28 January 2021 | By Hannah Balfour (Drug Target Review)

NeuroCOVID will be a resource of clinical information and biospecimens from people who experience neurological problems associated with SARS-CoV-2 infection.

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Melatonin could act as barrier against SARS-CoV-2 infection

28 January 2021 | By Victoria Rees (Drug Target Review)

Researchers have suggested using melatonin in a nasal spray to create a protective barrier against SARS-CoV-2 in pre-symptomatic patients.

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Biomarker in blood could determine severity of COVID-19

27 January 2021 | By Victoria Rees (Drug Target Review)

A study has shown that patients with severe COVID-19 have significantly elevated levels of M-MDSCs in their blood compared with healthy individuals.

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Rhesus macaques with SARS-CoV-2 develop promising immune response

25 January 2021 | By Victoria Rees (Drug Target Review)

A study has shown that the immune response of rhesus macaques with SARS-CoV-2 could be reproduced with a vaccine.

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SARS-CoV-2 triggers antibodies from previous coronavirus infections

22 January 2021 | By Victoria Rees (Drug Target Review)

A new study has shown that previous coronavirus infection may contribute to the immune response of patients infected with SARS-CoV-2.

blur viral particle surrounded by antibodies

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Artificial intelligence analyses how viruses evade the immune system

15 January 2021 | By Hannah Balfour (Drug Target Review)

The natural language processing model trained using viral protein sequence data was able to predict promising targets for vaccines against HIV, influenza and coronaviruses.

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SARS-CoV-2 infects CNS and damages brain tissue, study shows

13 January 2021 | By Victoria Rees (Drug Target Review)

Researchers have shown in cells and models that the central nervous system and neurons can become a target of SARS-CoV-2 infection.

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Macaques and baboons show success as models to study SARS-CoV-2

6 January 2021 | By Victoria Rees (Drug Target Review)

Researchers have shown rhesus macaques and baboons develop strong signs of acute viral infection from SARS-CoV-2, making them ideal models.

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Blood vessel damage likely causes neurological symptoms of COVID-19, finds study

4 January 2021 | By Hannah Balfour (Drug Target Review)

A new study suggests that inflammation and blood vessel damage may be the primary causes of neurological symptoms in COVID-19 patients, instead of the virus infecting the brain.

article

COVID-19 drug development based on boosting immunity

31 December 2020 | By Baidyanath Dash (G3 Systems)

Baidyanath Dash explains the two requirements for COVID-19 drug development: killing the virus and boosting immunity.

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