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Innovative algorithm could help advance single-cell genomics
Researchers have developed a novel algorithm, “scArches”, that can compare data on single-cell genomics to better understand diseases.
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Technical University of Munich (TUM)
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Synthetic peptides block atherosclerosis in pre-clinical studies
Researchers have synthesised peptides that function like a soluble chemokine receptor, blocking atherosclerosis in animal models.
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SARS-CoV-2 also uses neuropilin-1 to infect human cells
Researchers reveal that SARS-CoV-2 is more infectious than SARS-CoV because it can use both ACE2 and neuropilin-1 to infect cells.
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Artificial binding protein could be developed into a novel anti-viral or cancer therapy
Scientists have created an artificial protein able to recognise and bind cell surface carbohydrates with high affinity and selectivity.
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Novel label-free method enables imaging of metabolites
A label-free imaging technology has been developed by researchers, allowing them to investigate biomolecules such as metabolites, aiding in the study of drugs.
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Direct toxic action of beta-amyloid in Alzheimer’s patients identified
The cause and trigger of the large clumps of protein beta-amyloid found in the brains of early-stage Alzheimer's patients have been discovered.
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Using AI for error correction in single cell analyses
Researchers have developed algorithms that make it possible to predict and correct cells to identify genes...
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Administering hormones affects DNA
In an experiment with pigs, researchers have demonstrated for the first time that the administration of even extremely low doses of an endocrine disruptor - in this case, an endogenous oestrogen - leads to epigenetic changes in a pregnant sow’s DNA.
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PSMA PET/CT imaging provides precision radiation therapy for prostate cancer
A nuclear medicine scan may locate prostate cancer recurrence after radical prostatectomy early after disease recurrence and could help guide salvage radiotherapy...
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Proteome of the human heart mapped for the first time
Researchers have compiled an atlas of the heart to identify differences between healthy and diseased cells...
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Antibodies as ‘messengers’ in the nervous system
Antibodies are able to activate human nerve cells within milliseconds and hence modify their function.
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DFG €66 million funding for 15 new research training groups
The Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) is establishing 15 new Research Training Groups to further support early research...
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microRNA reduces stroke risk
The molecule microRNA-210 stabilises deposits in the carotid artery and can thus prevent them from tearing, and prevent dangerous blood clots from forming.
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Deep Learning predicts hematopoietic stem cell development
Autonomous driving, automatic speech recognition, and the game Go: Deep Learning is generating more and more public awareness.
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Next-Generation Sequencing In-Depth Focus 2016
NGS technologies have been employed in a wide range of areas in drug discovery, including drug target identification, biomarker discovery and biopharmaceutics development. Pushpanathan Muthuirulan of the National Institutes of Health gives us an overview of this in his article in our NGS In-Depth Focus. Meanwhile, the possibilities that RNA-Seq…
