List view / Grid view
St. Jude Children’s Research Hospital discovery of a regulatory enzyme working at the primary cilium could lead to treatments for the brain tumour medulloblastoma.
Scientists at The Scripps Research Institute (TSRI) have made another important advance in HIV vaccine design.
Researchers find key molecule that could lead to new therapies for anaemia and other iron disorders.
The science behind harnessing the immune system to fight cancer is complicated, but a University of Rochester Medical Center laboratory discovered a simple, practical way to use light and optics to steer killer immune cells toward tumours.
Investigators at Dartmouth's Geisel School of Medicine announced that two new studies of DAR-901, their investigational vaccine against tuberculosis (TB), have moved it to the forefront of new vaccines in development for global control of this deadly infectious disease.
Pluristem Therapeutics announced the promising results of its non-human primates (NHP) pilot study for PLX-R18 as a treatment for Acute Radiation Syndrome (ARS).
HTS can be carried out in a number of formats, ranging from simple biochemical (target-based) to whole animal screening assay formats. Horst Flotow, from Hit Discovery Constance, discusses the benefits and practicalities of, and recent progress in, whole animal screening. Madhu Lal-Nag, National Center for Advancing Translational Sciences, and Anton…
Amorsa Therapeutics' CSO, Michael Palfreyman, discusses how the party drug Ketamine can be used to target NMDA receptors and treat depression...
Ligands are useful tools for studying how proteins work in cells and could lead to the development of new drugs.
Medicinal marijuana is used frequently as a painkiller for a variety of ailments and diseases yet its psycho active side effects are seen by many as a significant disadvantage.
A new study led by scientists at the Scripps Research Institute (TSRI) sheds light on how the brain stores memories.
NGS technologies have been employed in a wide range of areas in drug discovery, including drug target identification, biomarker discovery and biopharmaceutics development. Pushpanathan Muthuirulan of the National Institutes of Health gives us an overview of this in his article in our NGS In-Depth Focus. Meanwhile, the possibilities that RNA-Seq…
30 November 2016 | By Niamh Louise Marriott, Digital Editor
Scientists at The Scripps Research Institute have developed a vaccine that blocks the pain-numbing effects of the opioid drugs in animal models...
28 November 2016 | By Niamh Louise Marriott, Digital Editor
This preclinical study should explore the potential of AIC649 to cure infections caused by hepatitis B virus (HBV) and is investigating the efficacy...
The discovery and development of novel drug candidates is a highly complex, time-consuming and expensive process. Pharmaceutical scientists and clinicians should, therefore, reevaluate and modify the existing standard platforms and increase their uptake of robust advanced technologies such as flow cytometry to overcome the bottlenecks in these processes...
