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Howard Hughes Medical Institute

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Study reveals how SARS-CoV-2 rewires human proteins for replication

1 July 2020 | By Victoria Rees (Drug Target Review)

A team of researchers has analysed how SARS-CoV-2 hijacks the proteins in its host cells to aid replication and infect nearby cells.

news

GREB1 gene potential drug target for prostate cancer treatment

16 January 2019 | By Drug Target Review

Researchers in the US have discovered how a gene involved in regulating hormone receptors, GREB1, may contribute to drug resistance in some prostate cancer patients.

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CRISPR used to prevent cancers tied to EBV and KSHV

13 November 2018 | By Drug Target Review

Researchers have discovered a possible path forward in preventing the development of cancers tied to two viruses, including the virus that causes infectious mononucleosis...

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DNA gets away: Scientists catch the rogue molecule that can trigger autoimmunity

22 February 2018 | By Drug Target Review

A research team has discovered the process - and filmed the actual moment - that can change the body’s response to a dying cell.

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CRISPR prevents hearing loss in mice

20 December 2017 | By Steve Bremer (Drug Target Review)

Researchers use CRISPR-Cas9 to target a mutation in the Tmc1 gene that causes the loss of hair cells in the inner ear.

news

Metabolic collaboration linked to Alzheimer’s disease

29 September 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have discovered that impairing a critical partnership between brain cells can lead to neurodegeneration...

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Gene therapy may lower risk for heart disease

29 August 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have tested whether a single injection of the gene, LeXis could slow down the development of heart disease...

news

Breakthrough method yields trove of neuronal subtypes and gene regulators

11 August 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have discovered a trove of neuronal subtypes and gene regulators, using a new method they developed called snmC-seq...

news

Researchers find key molecule that could lead to new anaemia therapies

17 May 2017 | By Niamh Marriott (Drug Target Review)

Researchers find key molecule that could lead to new therapies for anaemia and other iron disorders.

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Howard Hughes Medical Institute