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Gladstone Institutes

“Noisy” gene expression may help improve stem cell therapies

17 August 2021 | By Victoria Rees (Drug Target Review)

Researchers have identified a process that amplifies changes in gene expression, which could be harnessed to accelerate stem cell differentiation.

surface of several coronavirus particles

news

Novel target could treat both SARS-CoV-2 and other coronaviruses

10 December 2020 | By Hannah Balfour (Drug Target Review)

Scientists shows targeting cholesterol or phosphatidylinositol phosphate (PIP) could be a promising strategy to combat multiple coronaviruses.

brighly coloured neuron degenerating-neurodegeneration

article

Revealing the genetic signature of neurodegenerative disease

21 July 2020 | By Hannah Balfour (Drug Target Review)

Which immune cells contribute towards immune-induced neurodegeneration and how could this knowledge enable conditions such Alzheimer’s and multiple sclerosis to be treated?

news

Map of COVID-19 and human protein interactions reveals drug targets

24 March 2020 | By Victoria Rees (Drug Target Review)

Researchers have identified which SARS-CoV-2 proteins physically associate with proteins in human cells, revealing potential drug targets to treat the COVID-19 coronavirus.

news

Novel small molecule could treat Alzheimer’s disease and Dravet syndrome

16 January 2020 | By Hannah Balfour (Drug Target Review)

A new experimental drug was shown by researchers to restore natural brain rhythms in mouse models of Alzheimer’s and promote learning and memory.

news

Machine learning programme used to predict stem cell growth

21 November 2019 | By Victoria Rees (Drug Target Review)

Researchers have used machine learning to predict the conditions needed for stem cells to develop a certain way, which could be used to grow 3D organ models.

news

Drug targets for Dengue, Zika and Ebola viruses

14 December 2018 | By Drug Target Review

US researchers have identified possible drug targets for Dengue, Zika and Ebola viruses…

news

Immunotherapy targeting blood protein fibrin

16 October 2018 | By Iqra Farooq (Drug Target Review)

Targeting the fibrin protein could ensure that fibrin leaking through the blood-brain barrier does not cause inflammation or disease in the brain...

news

Researchers create first stem cells using CRISPR genome activation

23 January 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have turned skin cells from mice into stem cells by activating Sox2 and Oct4 using CRISPR technology...

news

Evotec, Gladstone Institutes and Dolby Family Ventures team up to find Alzheimer’s cure

24 July 2015 | By Victoria White

Evotec is teaming up with Cure Network Ventures and Dolby Family Ventures to identify new therapeutic approaches for Alzheimer’s disease...

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